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Validated All-in-One™ qPCR Primer for G3BP1(NM_005754.2) Search again
Product ID:
HQP000183
(click here to view gene annotation page)
Powered by BiozSpecies:
Human
Symbol:
Alias:
G3BP, HDH-VIII
Gene Description:
G3BP stress granule assembly factor 1
Target Gene Accession:
NM_005754.2(click here to view gene page)
Estimated Delivery:
Approximately 1-3 weeks, but may vary. Please email sales@genecopoeia.com or call 301-762-0888 to confirm ETA.
Important Note:
By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.
Summary
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion.
Gene References into function
- involvement of cellular protein G3BP in transcription of intermediate stage genes may regulate the transition between early and late phases of vaccinia virus replication
- G3BPs are scaffolding proteins linking signal transduction to RNA metabolism (review)
- Hepatitis C virus viral gene and proteins may regulate the presence of host cellular proteins in detergent resistant membrane
- Caprin-1/G3BP-1 complex is likely to regulate the transport and translation of mRNAs of proteins involved with synaptic plasticity in neurons
- Both G3BP1 and G3BP2 isoforms may act as negative regulators of tumor suppressor protein p53.
- The expression of G3BP and RhoC protein is closely related to the lymph node metastasis and survival in esophageal squamous carcinoma (ESC) patients. G3BP and RhoC proteins can be considered as predictors of prognosis in ESC patients.