All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

RNA Interference (RNAi) solution

GeneCopoeia RNAi solution include tools for your gene knockdown, gene regulation, and target validation studies. Tools for transient and stable transfection, and transduction (infection) into a broad range of cell types including the difficult-to-transfect, neuronal, primary as well as conventional dividing cells are available.

shRNA – gene knockdown Lentiviral and non-viral vector-based clones (plasmids) for genome-wide human, mouse and rat	Precursor miRNA – miRNA overexpression Lentiviral and non-viral vector-based clones (plasmids) for all known human, mouse and rat miRNA
miRNA inhibitors – miRNA knockdown Lentiviral and non-viral vector-based clones (plasmids); and synthetic oligonucleotides for all known human, mouse and rat miRNA	miRNA 3’ UTR targets – target gene validation Luciferase vector-based clones (plasmids) for genome-wide human, mouse and rat genes
miRNA qRT-PCR – miRNA detection and quantification Validated miRNA specific primers and SYBR® Green based detection kits

Figure 1: Vector-based shRNA or microRNA RNAi mechanism

RNA Interference (RNAi) solution

shRNA – gene knockdown

Precursor miRNA – miRNA overexpression

miRNA inhibitors – miRNA knockdown

miRNA 3’ UTR targets – target gene validation

miRNA qRT-PCR – miRNA detection and quantification