| Catalog # |
hRP-T2991-EF012 |
| Size |
100 μg |
| Protein Name |
Human histone-lysine N-methyltransferase |
| Protein Symbol |
SETMAR |
| Original Source |
Homo sapiens |
| Expression System |
E.coli |
| GenBank Accession # |
BC008931.1 |
| Uniprot Accession # |
E7EN68 |
| Description |
Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 'Lys-36'. Has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Has DNA nicking activity. Has in vivo end joining activity and may mediate genomic integration of foreign DNA. |
| Application |
WB, ELISA, IP, antibody production, protein array |
| Fusion tag |
N-His |
| Peptide Length |
358aa(including fusion tag) |
| Molecular Weight |
42.1kDa(including fusion tag) |
| pI |
8.1 |
| Activity |
NA |
| Storage |
Storage buffer: 20mM Tris.Cl, 50mM NaCl, 50% Glycerol, pH9.0. Store at -80°C and avoid repeated freeze-thaw cycles. |
| Purity |
|
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