Recombinant Human S100A6 Protein Data Sheet

Catalog #	hRP-A0791-EF012
Size	100 μg
Protein Name	Human S100 calcium binding protein A6
Protein Symbol	S100A6
Original Source	Homo sapiens
Expression System	E.coli
GenBank Accession #	NM_014624.2
Uniprot Accession #	P06703
Description	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-bindingmotifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
Application	WB, ELISA, IP, antibody production, protein array
Fusion tag	N-His
Peptide Length	105aa(including fusion tag)
Molecular Weight	10.2kDa(including fusion tag)
pI	5.1
Activity	NA
Storage	Storage buffer: 20mM Tris.Cl, 50mM NaCl, 50% Glycerol, pH8.0. Store at -80°C and avoid repeated freeze-thaw cycles.
Purity

Reference:

• S100A6 - new facts and features.
• Involvement of S100A6 (calcyclin) and its binding partners in intracellular signaling pathways.
• The Role of S100A6 in Pancreatic Cancer Development and Its Clinical Implication as a Diagnostic Marker and Therapeutic Target
• Structure of the S100A6 complex with a fragment from the C-terminal domain of Siah-1 interacting protein: A novel mode for S100 protein target recognition