Recombinant Human IL1B Protein Data Sheet


Catalog # hRP-A0180-ES131
Size 25 μg
Protein Name Human interleukin-1 beta
Protein Symbol IL1B
Original Source Homo sapiens
Expression System E.coli
GenBank Accession # X02532.1
Uniprot Accession # P01584
Description The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Application WB, ELISA, IP, antibody production, protein array
Fusion tag Trx-His-SUMO
Peptide Length 493aa(including fusion tag)
Molecular Weight 55.6kDa(including fusion tag)
pI 4.8
Activity NA
Storage Storage buffer: 1XPBS. Store at -80°C and avoid repeated freeze-thaw cycles.
 

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