EGR1 transcriptional response element (TRE) clone

EGR1 transcriptional response element(TRE) clone for EGR1 pathway
EGR1 transcriptional response element(TRE) clone for EGR1 pathway
Transcriptional response element(TRE) negative control clone
Transcriptional response element(TRE) negative control clone
GAPDH positive control clone
GAPDH positive control clone
Secreted alkaline phosphatase (SEAP)<br />Expression clone
Secreted alkaline phosphatase (SEAP)
Expression clone

EGR1 transcriptional response element(TRE) clone for EGR1 pathway Transcriptional response element(TRE) negative control clone GAPDH positive control clone Secreted alkaline phosphatase (SEAP)
Expression clone

Price: $350.00 $350.00 $375.00 $395.00
Catalog#:
  • TR107
  • TR001
  • GAPDH-PG02
  • SEAP-PA01
Size: pEZX-PG02 pEZX-PG02 pEZX-PG02 pEZX-PA01
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Introduction GeneCopoeia’s GLuc-ON™ EGR1 transcriptional response element (TRE) clone enables analysis of the effects on genes regulated by early growth respionse protein 1 (EGR1), such as  transforming growth factor-beta-1 (TGFB1) and fibronectin (FN1). EGR1 is a transcription factor that responds to mitogenic stimulation. EGR1 regulates many processes, such as neuron activity, wound healing, apopotosis, and angiogenesis, and is known to both suppress and promote tumor growth. The GLuc-ON™ EGR1 TRE clone contains tandem repeats of an EGR1 binding site upstream of a minimal promoter and secreted Gaussia luciferase reporter gene, which allows robust and sensitive analysis without lysing the cells.  The EGR1 response elements are engineered to provide strong activation with low background (Figure 1). The GLuc-ON™ EGR1 TRE clone is provided as transfection-ready DNA. Negative (non-activating), positive (constitutively-activted) and normalization (secreated alkaline phosphatase) control clones are also available for purchase.