Monthly Archives: April 2019

BlazeTaq™ Probe qPCR Mix

BlazeTaq™ Probe qPCR mix is designed for highly sensitive and accurate quantitative PCR (qPCR) that uses hydrolysis probes and DNA as starting material. The kit is supplied with a ready-to-use 5X master mix with a hot-start Taq DNA polymerase, dNTP and all optimized buffer components. Tests show that the BlazeTaq™ Probe qPCR Mix is compatible with diverse real-time PCR instruments and outperforms competitors' products on the sensitivity and specificity of cDNA and genomic DNA detection.​               ​   Order informatio......
Posted in qPCR products

MSI

Introduction Resources Related services Introduction MSI (Microsatellite Instability) is failure to correct the errors that spontaneously occur during DNA replication caused by DNA mismatch repair deficiency (dMMR), resulting in the accumulation of chromosomal mutations at certain repetitive DNA motifs as microsatellites. GeneCopoeia's MSI analysis service uses the PrecisionPlex™ MSI Detection System, which consists of a unique combination of seven mononucleotide microsatellite loci that can potentially lead to more sensitive and specific results compared to competito......
Posted in Custom services

STR

Short tandem repeat (STR) profiling allows customers to confirm the identity of a cell line and whether it is free of contamination from other cell lines and microbes. It is estimated 15-20% of cell cultures are cross-contaminated or misidentified, leading to lost time, money and retraction of previous publications due to invalid data. NIH recommends that all cell lines are authenticated before publication. Nature mandates STR fingerprinting data for papers reporting new human embryonic stem cell lines. GeneCopoeia's STR profiling service uses the PrecisionPlex™ 25 S......
Posted in Custom services

Cell Line Characterization & Authentication

Introduction Resources Introduction R&D involving the use of cell lines requires a good understanding of the purity, species of origin, chromosomal and genetic characteristics of the cell lines used. Cultured cell lines in the lab are susceptible to contamination by microbes, mycoplasma and other cells, thereby demanding periodic monitoring for characteristics to authenticate the cell line identity. GeneCopoeia offers cell line characterization reagent kits and services that involve testing for a combination of important genetic markers, including chromosomes, DNA fingerprints, ......
Posted in Custom services