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shRNA Clone Collection Publications

View selected publications citing GeneCopoeia’s OMICSLINK™ shRNA clone sets from the recent literature

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Reagents and Kits Publications

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  • Bid, HK. et al. (2016) The Bromodomain BET inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood Sarcoma. Molecular Cancer Therapeutics,Published OnlineFirst February 23, 2016; doi: 10.1158/1535-7163.MCT-15-0567. [AP-1 activity assay kit]
  • Wang, S., et al. (2016). Pharmacological evidence: a new therapeutic approach to the treatment of chronic heart failure through SUR2B/Kir6.1 channel in endothelial cells. Acta Pharmacologica Sinica doi: 10.1038/aps.2016.118 [RNAzol®RT reagent]

 

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ORF cDNA Clone Publications

View selected publications citing GeneCopoeia’s ORF cDNA clones from the recent literature

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Lentiviral Solutions Publications

View selected publications citing GeneCopoeia’s lentiviral products from the recent literature

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Recombination Cloning Technology

Recombination cloning technology is based on the site specific recombination reaction of phage lambda, and is the same principle as Gateway® technology, an efficient biochemical process that conserves genetic information (see Figure 1). The transmission of an ORF from EZShuttle Gateway® PLUS ORF Clones to a pEZ™ or Gateway® Destination Vector is a one step simple and rapid operation (60 minutes at room temperature), which saves a significant amount of time and effort from the tedious, multiple step, sub-cloning process involving enzyme digestions, ligations, gel electrophoresis and purification (see Figure 2). Furthermore, GeneCopoeia provides a family of pEZ™ vectors that contain different promoters and fusion-tags that meet the distinct requirements for production and purification of desired recombinant proteins in several expression hosts.

 

Figure 1. Site specific recombination reaction of phage lambda, Click on the image to see enlarged image Figure 2. One step transmission of an ORF from EZShuttle™ Gateway PLUS ORF clones to a pEZ™ or Gateway destination vector. Click on the image to see enlarged image


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Note: Gateway® is a registered trademark of Life Technologies..