Monthly Archives: March 2019

Cell Immortalization Reagents

Primary cells undergo a finite number of population doublings and reach a state called replicative senescence after limited cell divisions. GeneCopoeia’s Cell Immortalization Reagents use recombinant lentivirus carrying genes, such as the simian virus 40 (SV40) T antigen, the human telomerase reverse transcriptase protein (hTERT), CDK4, HOXB, HOXA, cMyc, Bmi1 and HPV-16 E6/E7 to induce immortalization and significantly prolong primary cells' lifespan. Order information Product details Related products Resources Order information Buy......
Posted in Lentiviral system

BlazeTaq™ Probe One-Step RT-qPCR Kit

GeneCopoeia's BlazeTaq™ Probe One-Step RT-qPCR kit is based on quantitative reverse transcription PCR (RT-qPCR) that uses RNA as starting material. It offers a convenient master mix to convert RNA to DNA and quantify expression levels in a one step reaction using hydrolysis probes. The kit is supplied with reverse transcriptase and a 5X master mix with a hot-start Taq DNA polymerase, dNTP and all required buffer components. Tests show that the BlazeTaq™ Probe One-Step RT-qPCR kit is compatible with diverse real-time PCR instruments and outperforms competitors' ......
Posted in qPCR products

AKT E17K Reference Standard

The AKT E17K Reference Standard is FFPE derived from a highly characterized homozygous diploid HCT116 cell line, genetically modified with advanced genome editing technology to include the mutation E17K in AKT on both chromosomes. The variant allele frequency (VAF) is 100%, and can be used for quality control in the FFPE DNA extraction process. This reference standard can be used to assess the performance of your NGS, sanger sequencing and qPCR assay, including the limit of detection, accuracy, and precision. .accordion_h {background-color: #f9f9f9; c......
Posted in Products

cKIT D816V Reference Standard

The cKIT D816V Reference Standard is FFPE derived from a highly characterized homozygous diploid HCT116 cell line, genetically modified with advanced genome editing technology to include the mutation D816V in cKIT on both chromosomes. The variant allele frequency (VAF) is 100%, and can be used for quality control in the FFPE DNA extraction process. This reference standard can be used to assess the performance of your NGS, sanger sequencing and qPCR assay, including the limit of detection, accuracy, and precision. .accordion_h {background-color: #f9f9f......
Posted in Products

BRAF V600E Reference Standard

The BRAF V600E Reference Standard is FFPE derived from a highly characterized homozygous diploid HCT116 cell line, genetically modified with advanced genome editing technology to include the mutation V600E in BRAF on both chromosomes. The variant allele frequency (VAF) is 100%, and can be used for quality control in the FFPE DNA extraction process. This reference standard can be used to assess the performance of your NGS, sanger sequencing and qPCR assay, including the limit of detection, accuracy, and precision. .accordion_h {background-color: #f9f9f......
Posted in Products

KRAS G13C Reference Standard

The KRAS G13C Reference Standard is FFPE derived from a highly characterized homozygous diploid HCT116 cell line, genetically modified with advanced genome editing technology to include the mutation G13C in KRAS on both chromosomes. The variant allele frequency (VAF) is 100%, and can be used for quality control in the FFPE DNA extraction process. This reference standard can be used to assess the performance of your NGS, sanger sequencing and qPCR assay, including the limit of detection, accuracy, and precision. .accordion_h {background-color: #f9f9f9;......
Posted in Products

EGFR T790M C797S Reference Standard

The EGFR T790M C797S Reference Standard is FFPE derived from a highly characterized homozygous diploid HCT116 cell line, genetically modified with advanced genome editing technology to include the mutation T790M and C797S in EGFR on both chromosomes. The variant allele frequency (VAF) is 100%, and can be used for quality control in the FFPE DNA extraction process. This reference standard can be used to assess the performance of your NGS, sanger sequencing and qPCR assay, including the limit of detection, accuracy, and precision. .accordion_h {backgrou......
Posted in Products

EGFR T790M Reference Standard

The EGFR T790M Reference Standard is FFPE derived from a highly characterized homozygous diploid HCT116 cell line, genetically modified with advanced genome editing technology to include the mutation T790M in EGFR on both chromosomes. The variant allele frequency (VAF) is 100%, and can be used for quality control in the FFPE DNA extraction process. This reference standard can be used to assess the performance of your NGS, sanger sequencing and qPCR assay, including the limit of detection, accuracy, and precision. .accordion_h {background-color: #......
Posted in Products

EGFR L858R Reference Standard

The EGFR L858R Reference Standard is FFPE derived from a highly characterized heterozygous diploid HCT116 cell line, genetically modified with advanced genome editing technology to include the mutation L858R in EGFR on one of the two chromosomes. The variant allele frequency (VAF) is 50%, and can be used for quality control in the FFPE DNA extraction process. This reference standard can be used to assess the performance of your NGS, sanger sequencing and qPCR assay, including the limit of detection, accuracy, and precision. .accordion_h {background-co......
Posted in Products

Wild type HCT116 Reference Standard

The Wild type Parental HCT116 Reference Standard is FFPE derived from a highly characterized diploid HCT116 cell line. This reference standard can be used to assess the performance of your NGS, sanger sequencing and qPCR assay, including the limit of detection, accuracy, and precision. .accordion_h {background-color: #f9f9f9; color: black; cursor: pointer; margin:0px; padding: 10px; width: 100%; border-color:#c1c1c1; border-width:2px; border-radius: 5px; text-align: left; margin-bottom:5px; outline: none; font-size: 16px; font-weight: bold; transition: 0.2s;}.active, .accordi......
Posted in Products