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Ion channels

by | Mar 22, 2024 | Clone sets

Introduction

Ion channels are transmembrane proteins with special functions on cell membranes (including cytoplasmic and intracellular membranes). Since charged ions cannot freely pass through the lipid bilayer, they can only be transported through ion channels. Ion channels exist in the membranes of all cells, and their distribution and activity are very important for the excitability and function of cells and tissues.
A variety of ion channels exist in human tissues, and a variety of subtypes of each channel, such as calcium channels including members of KCTD10, KCNMA1, KCNIP2, SCN5A, and CHRNA3, potassium channels including members of TASK-1, TASK-3, TREK-1, MthK, and other members, each with specific nucleic sequences. They are both important factors in physiological regulation and can be used as targets for drug action to develop new specific drugs.

Clone set information

Cat. No. Old Cat. No. Species Gene Vector Vector Type Price
OC-GF010-M02 OC-HIC-M02 Human 448 pReceiver-M02 Expression-ready Non-viral Inquire
OC-GF010-M35 OC-HIC-M35 Human 448 pReceiver-M35 Expression-ready Non-viral Inquire
OC-GF010-M98 OC-HIC-M98 Human 448 pReceiver-M98 Expression-ready Non-viral Inquire
OC-GF010-Lv105 OC-HIC-Lv105 Human 448 pReceiver-Lv105 Expression-ready Lentiviral Inquire
OC-GF010-Lv242 OC-HIC-Lv242 Human 448 pReceiver-Lv242 Expression-ready Lentiviral Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.
Symbol Accession Species Description ORF length(bp) Product ID
GABRB3 NM_000814.6 Human Homo sapiens gamma-aminobutyric acid type A receptor subunit beta3 (GABRB3), transcript variant 1, mRNA. 1422 GC-A0053
CHRNA5 NM_000745.4 Human Homo sapiens cholinergic receptor nicotinic alpha 5 subunit (CHRNA5), transcript variant 1, mRNA. 1407 GC-A0055
KCNA5 NM_002234.4 Human Homo sapiens potassium voltage-gated channel subfamily A member 5 (KCNA5), mRNA. 1842 GC-A0121
GABRA1 NM_001127643.2 Human Homo sapiens gamma-aminobutyric acid type A receptor subunit alpha1 (GABRA1), transcript variant 2, mRNA. 1371 GC-A0140
ANXA7 NM_001156.5 Human Homo sapiens annexin A7 (ANXA7), transcript variant 1, mRNA. 1401 GC-A0189
KCNA2 NM_004974.4 Human Homo sapiens potassium voltage-gated channel subfamily A member 2 (KCNA2), transcript variant 1, mRNA. 1500 GC-A0194
CACNG1 NM_000727.4 Human Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 1 (CACNG1), mRNA. 669 GC-A0209
GABRA5 NM_000810.4 Human Homo sapiens gamma-aminobutyric acid type A receptor subunit alpha5 (GABRA5), transcript variant 1, mRNA. 1389 GC-A0216
SCN1B NM_001037.5 Human Homo sapiens sodium voltage-gated channel beta subunit 1 (SCN1B), transcript variant a, mRNA. 657 GC-A0221
GRIN1 NM_007327.4 Human Homo sapiens glutamate ionotropic receptor NMDA type subunit 1 (GRIN1), transcript variant GluN1-1a, mRNA. 2817 GC-A0292
VDAC1 NM_003374.3 Human Homo sapiens voltage dependent anion channel 1 (VDAC1), transcript variant 1, mRNA. 852 GC-A0299
KCNA6 NM_002235.5 Human Homo sapiens potassium voltage-gated channel subfamily A member 6 (KCNA6), transcript variant 4, mRNA. 1590 GC-A0329
GABRG2 NM_000816.3 Human Homo sapiens gamma-aminobutyric acid type A receptor gamma2 subunit (GABRG2), transcript variant 2, mRNA. 1404 GC-A0402
CHRM2 NM_001006630.2 Human Homo sapiens cholinergic receptor muscarinic 2 (CHRM2), transcript variant 1, mRNA. 1401 GC-A0448
GLRA2 NM_001118885.2 Human Homo sapiens glycine receptor alpha 2 (GLRA2), transcript variant 2, mRNA. 1359 GC-A0526
CHRND NM_000751.3 Human Homo sapiens cholinergic receptor nicotinic delta subunit (CHRND), transcript variant 1, mRNA. 1554 GC-A0532
GRIK2 NM_021956.5 Human Homo sapiens glutamate ionotropic receptor kainate type subunit 2 (GRIK2), transcript variant 1, mRNA. 2727 GC-A0588
CNGB1 NM_001135639.2 Human Homo sapiens cyclic nucleotide gated channel subunit beta 1 (CNGB1), transcript variant 2, mRNA. 900 GC-A0599
KCNJ2 NM_000891.3 Human Homo sapiens potassium inwardly rectifying channel subfamily J member 2 (KCNJ2), mRNA. 1284 GC-A0609
KCNJ6 NM_002240.5 Human Homo sapiens potassium inwardly rectifying channel subfamily J member 6 (KCNJ6), mRNA. 1272 GC-A0611
GABRA4 NM_000809.4 Human Homo sapiens gamma-aminobutyric acid type A receptor subunit alpha4 (GABRA4), transcript variant 1, mRNA. 1665 GC-A0620
GLRB NM_001166060.1 Human Homo sapiens glycine receptor beta (GLRB), transcript variant 2, mRNA. 1494 GC-A0627
KCNAB2 NM_001199861.2 Human Homo sapiens potassium voltage-gated channel subfamily A regulatory beta subunit 2 (KCNAB2), transcript variant 4, mRNA. 1104 GC-A0628
KCNK1 NM_002245.4 Human Homo sapiens potassium two pore domain channel subfamily K member 1 (KCNK1), mRNA. 1011 GC-A0629
CHRNB2 NM_000748.3 Human Homo sapiens cholinergic receptor nicotinic beta 2 subunit (CHRNB2), mRNA. 1509 GC-A0648
CLCN2 NM_004366.6 Human Homo sapiens chloride voltage-gated channel 2 (CLCN2), transcript variant 1, mRNA. 2697 GC-A0687
CHRNA4 NM_000744.7 Human Homo sapiens cholinergic receptor nicotinic alpha 4 subunit (CHRNA4), transcript variant 1, mRNA. 1884 GC-A0724
SCNN1G NM_001039.4 Human Homo sapiens sodium channel epithelial 1 subunit gamma (SCNN1G), mRNA. 1950 GC-A0726
AQP4 NM_004028.5 Human Homo sapiens aquaporin 4 (AQP4), transcript variant 2, mRNA. 906 GC-A0762
CACNB3 NM_000725.4 Human Homo sapiens calcium voltage-gated channel auxiliary subunit beta 3 (CACNB3), transcript variant 1, mRNA. 1455 GC-A0872
GRIK1 NM_000830.6 Human Homo sapiens glutamate ionotropic receptor kainate type subunit 1 (GRIK1), transcript variant 1, mRNA. 2757 GC-A0927
GABRB2 NM_000813.3 Human Homo sapiens gamma-aminobutyric acid type A receptor subunit beta2 (GABRB2), transcript variant 2, mRNA. 1425 GC-A0939
CHRNA7 NM_000746.6 Human Homo sapiens cholinergic receptor nicotinic alpha 7 subunit (CHRNA7), transcript variant 1, mRNA. 1509 GC-A0962
KCNH2 NM_000238.4 Human Homo sapiens potassium voltage-gated channel subfamily H member 2 (KCNH2), transcript variant 1, mRNA. 3480 GC-A1128
KCNJ4 NM_004981.2 Human Homo sapiens potassium inwardly rectifying channel subfamily J member 4 (KCNJ4), transcript variant 2, mRNA. 1338 GC-A1149
GABRA6 NM_000811.3 Human Homo sapiens gamma-aminobutyric acid type A receptor subunit alpha6 (GABRA6), mRNA. 1362 GC-A1235
CHRM1 NM_000738.3 Human Homo sapiens cholinergic receptor muscarinic 1 (CHRM1), mRNA. 1383 GC-A1293
ATP4B NM_000705.4 Human Homo sapiens ATPase H+/K+ transporting subunit beta (ATP4B), mRNA. 876 GC-C0018
ATP1A2 NM_000702.4 Human Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA. 3063 GC-C0098
ATP2B4 NM_001684.5 Human Homo sapiens ATPase plasma membrane Ca2+ transporting 4 (ATP2B4), transcript variant 2, mRNA. 3618 GC-C0208
ATP1B1 NM_001677.4 Human Homo sapiens ATPase Na+/K+ transporting subunit beta 1 (ATP1B1), mRNA. 912 GC-C0229
AQP2 NM_000486.5 Human Homo sapiens aquaporin 2 (AQP2), mRNA. 816 GC-C0649
CLCN3 NM_001829.4 Human Homo sapiens chloride voltage-gated channel 3 (CLCN3), transcript variant b, mRNA. 2457 GC-E0037
GABRA2 NM_001114175.3 Human Homo sapiens gamma-aminobutyric acid type A receptor subunit alpha2 (GABRA2), transcript variant 2, mRNA. 1356 GC-E0263
GABRB2 NM_021911.3 Human Homo sapiens gamma-aminobutyric acid type A receptor subunit beta2 (GABRB2), transcript variant 1, mRNA. 1539 GC-E0533
CACNA2D3 NM_018398.2 Human Homo sapiens calcium voltage-gated channel auxiliary subunit alpha2delta 3 (CACNA2D3), mRNA. 3276 GC-E0680
SCN4B NM_174934.4 Human Homo sapiens sodium voltage-gated channel beta subunit 4 (SCN4B), transcript variant 1, mRNA. 687 GC-E0734
ATP2A1 NM_004320.6 Human Homo sapiens ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 (ATP2A1), transcript variant a, mRNA. 2985 GC-E1171
TPCN1 NM_017901.6 Human Homo sapiens two pore segment channel 1 (TPCN1), transcript variant 2, mRNA. 2451 GC-E1339
KCNK18 NM_181840.1 Human Homo sapiens potassium two pore domain channel subfamily K member 18 (KCNK18), mRNA. 1155 GC-E1355

Histone modification enzymes

by | Mar 22, 2024 | Clone sets

Introduction

Histone modification refers to the dynamic process by which histones are modified through methylation, acetylation, phosphorylation, adenylation, ubiquitination, ADP-ribosylation and other processes that are facilitated by specific enzymes.
Histone modifying enzymes include: histone acetyltransferase HAT and histone deacetylase HDAC for controlling acetylation; histone methyltransferases HMTs/KMTs, protein arginine methyltransferases PRMTs, and lysine demethylases KDMs for methylation; ubiquitylating histone ubiquitin ligases and deubiquitylating enzymes, etc. Histone modifications are a major form of epigenetics and play a crucial role in regulating genetic expression and phenotype. For example, histone modifications regulate the expression of nervous system-associated genes, which are crucial for the normal function of the nervous system, adaptive regulation, and the progression of neurodegenerative diseases, with distinct roles depending on the type of histone modification.

Clone set information

Cat. No. Old Cat. No. Species Gene Vector Vector Type Price
OC-GF009-M02 OC-HHM-M02 Human 107 pReceiver-M02 Expression-ready Non-viral Inquire
OC-GF009-M35 OC-HHM-M35 Human 107 pReceiver-M35 Expression-ready Non-viral Inquire
OC-GF009-M98 OC-HHM-M98 Human 107 pReceiver-M98 Expression-ready Non-viral Inquire
OC-GF009-Lv105 OC-HHM-Lv105 Human 107 pReceiver-Lv105 Expression-ready Lentiviral Inquire
OC-GF009-Lv242 OC-HHM-Lv242 Human 107 pReceiver-Lv242 Expression-ready Lentiviral Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.
Symbol Accession Species Description ORF length(bp) Product ID
HDAC9 NM_014707.4 Human Homo sapiens histone deacetylase 9 (HDAC9), transcript variant 3, mRNA. 1773 GC-E0013
DOT1L NM_032482.3 Human Homo sapiens DOT1 like histone lysine methyltransferase (DOT1L), mRNA. 4614 GC-E0567
HDAC1 NM_004964.3 Human Homo sapiens histone deacetylase 1 (HDAC1), mRNA. 1449 GC-I0488
KAT7 NM_007067.4 Human Homo sapiens lysine acetyltransferase 7 (KAT7), transcript variant 1, mRNA. 1836 GC-T0265
HDAC3 NM_003883.4 Human Homo sapiens histone deacetylase 3 (HDAC3), transcript variant 2, mRNA. 1287 GC-T1848
SIRT2 NM_012237.4 Human Homo sapiens sirtuin 2 (SIRT2), transcript variant 1, mRNA. 1170 GC-T1930
HDAC11 NM_024827.4 Human Homo sapiens histone deacetylase 11 (HDAC11), transcript variant 1, mRNA. 1044 GC-T2114
SETD7 NM_030648.4 Human Homo sapiens SET domain containing 7, histone lysine methyltransferase (SETD7), transcript variant 1, mRNA. 1101 GC-T3450
HDAC10 NM_032019.6 Human Homo sapiens histone deacetylase 10 (HDAC10), transcript variant 1, mRNA. 2010 GC-T3601
SUV39H1 NM_003173.4 Human Homo sapiens SUV39H1 histone lysine methyltransferase (SUV39H1), transcript variant 2, mRNA. 1239 GC-U1202
HDAC4 NM_006037.4 Human Homo sapiens histone deacetylase 4 (HDAC4), transcript variant 2, mRNA. 3255 GC-U1371
HDAC6 NM_001321230.2 Human Homo sapiens histone deacetylase 6 (HDAC6), transcript variant 7, mRNA. 441 GC-V0819
HDAC7 NM_001098416.4 Human Homo sapiens histone deacetylase 7 (HDAC7), transcript variant 4, mRNA. 2865 GC-Z1602
HDAC5 NM_001015053.2 Human Homo sapiens histone deacetylase 5 (HDAC5), transcript variant 3, mRNA. 3372 GC-Z4127
HDAC7 NM_015401.5 Human Homo sapiens histone deacetylase 7 (HDAC7), transcript variant 1, mRNA. 2976 GC-Z4621
HDAC9 NM_058176.2 Human Homo sapiens histone deacetylase 9 (HDAC9), transcript variant 1, mRNA. 3036 GC-E2449
HDAC9 NM_178425.4 Human Homo sapiens histone deacetylase 9 (HDAC9), transcript variant 5, mRNA. 3210 GC-E2498
SIRT2 NM_030593.3 Human Homo sapiens sirtuin 2 (SIRT2), transcript variant 2, mRNA. 1059 GC-T3000
EDF1 NM_003792.4 Human Homo sapiens endothelial differentiation related factor 1 (EDF1), transcript variant alpha, mRNA. 447 GC-U0296
ELP3 NM_018091.6 Human Homo sapiens elongator acetyltransferase complex subunit 3 (ELP3), transcript variant 1, mRNA. 1644 GC-V0251
OGA NM_012215.5 Human Homo sapiens O-GlcNAcase (OGA), transcript variant 1, mRNA. 2751 GC-U1247
CDY1 NM_170723.2 Human Homo sapiens chromodomain Y-linked 1 (CDY1), transcript variant 1, mRNA. 1623 GC-Z4039
CDYL NM_004824.4 Human Homo sapiens chromodomain Y like (CDYL), transcript variant 1, mRNA. 1635 GC-Z1307
CLOCK NM_001267843.2 Human Homo sapiens clock circadian regulator (CLOCK), transcript variant 1, mRNA. 2541 GC-U0240
ELP4 NM_019040.5 Human Homo sapiens elongator acetyltransferase complex subunit 4 (ELP4), transcript variant 1, mRNA. 1275 GC-T1173
GTF3C4 NM_012204.4 Human Homo sapiens general transcription factor IIIC subunit 4 (GTF3C4), transcript variant 1, mRNA. 2469 GC-U0508
NCOA3 NM_006534.4 Human Homo sapiens nuclear receptor coactivator 3 (NCOA3), transcript variant 2, mRNA. 4263 GC-Z3016
NCOA3 NM_181659.3 Human Homo sapiens nuclear receptor coactivator 3 (NCOA3), transcript variant 1, mRNA. 4275 GC-Z5301
USP22 NM_015276.2 Human Homo sapiens ubiquitin specific peptidase 22 (USP22), mRNA. 1578 GC-H1929
MTA2 NM_004739.4 Human Homo sapiens metastasis associated 1 family member 2 (MTA2), transcript variant 1, mRNA. 2007 GC-U1472
EZH1 NM_001991.5 Human Homo sapiens enhancer of zeste 1 polycomb repressive complex 2 subunit (EZH1), transcript variant 1, mRNA. 2244 GC-M0269
EZH2 NM_004456.5 Human Homo sapiens enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2), transcript variant 1, mRNA. 2256 GC-Z0388
EZH2 NM_152998.3 Human Homo sapiens enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2), transcript variant 2, mRNA. 2124 GC-Z5167
PRDM7 NM_001098173.2 Human Homo sapiens PR/SET domain 7 (PRDM7), mRNA. 1479 GC-H1723
KMT5B NM_016028.4 Human Homo sapiens lysine methyltransferase 5B (KMT5B), transcript variant 2, mRNA. 1182 GC-Z4641
KMT5B NM_017635.5 Human Homo sapiens lysine methyltransferase 5B (KMT5B), transcript variant 1, mRNA. 2658 GC-Z4681
KMT5C NM_032701.4 Human Homo sapiens lysine methyltransferase 5C (KMT5C), mRNA. 1389 GC-Z1256
NSD2 NM_133335.4 Human Homo sapiens nuclear receptor binding SET domain protein 2 (NSD2), transcript variant 3, mRNA. 4098 GC-W0268
NSD2 NM_007331.2 Human Homo sapiens nuclear receptor binding SET domain protein 2 (NSD2), transcript variant 8, mRNA. 1890 GC-X0368
NSD2 NM_133334.2 Human Homo sapiens nuclear receptor binding SET domain protein 2 (NSD2), transcript variant 7, mRNA. 1944 GC-Z5057
NSD3 NM_023034.2 Human Homo sapiens nuclear receptor binding SET domain protein 3 (NSD3), transcript variant long, mRNA. 4314 GC-V1657
NSD3 NM_017778.3 Human Homo sapiens nuclear receptor binding SET domain protein 3 (NSD3), transcript variant short, mRNA. 1938 GC-X0597
JMJD6 NM_015167.3 Human Homo sapiens jumonji domain containing 6, arginine demethylase and lysine hydroxylase (JMJD6), transcript variant 2, mRNA. 1212 GC-E2113
SUV39H2 NM_001193426.2 Human Homo sapiens SUV39H2 histone lysine methyltransferase (SUV39H2), transcript variant 4, mRNA. 693 GC-T7836
PRMT5 NM_006109.5 Human Homo sapiens protein arginine methyltransferase 5 (PRMT5), transcript variant 1, mRNA. 1914 GC-V1247
KDM1A NM_001009999.3 Human Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA. 2631 GC-E2594
KDM4C NM_001146695.4 Human Homo sapiens lysine demethylase 4C (KDM4C), transcript variant 3, mRNA. 2442 GC-Z7106
KDM4C NM_001146696.2 Human Homo sapiens lysine demethylase 4C (KDM4C), transcript variant 4, mRNA. 2508 GC-H4294
KDM4E NM_001161630.1 Human Homo sapiens lysine demethylase 4E (KDM4E), mRNA. 1521 GC-H4383
KDM5A NM_001042603.3 Human Homo sapiens lysine demethylase 5A (KDM5A), mRNA. 5073 GC-H3429

Histones

by | Mar 22, 2024 | Clone sets

Introduction

Histones are alkaline proteins found in the chromatin of eukaryotic and prokaryotic cells, which form the structure of nucleosomes and are water-soluble together with DNA. They are mainly divided into five categories depending on their amino acid composition and molecular weight: H1/H5, H2A, H2B, H3, and H4.
Histones are rich in positively charged basic amino acids and can interact with the negatively charged phosphate groups in DNA. Histones have the functions of filling proteins and regulating chromatin, which is mainly realized through their modification.

Clone set information

Cat. No. Old Cat. No. Species Gene Vector Vector Type Price
OC-GF008-M02 OC-HHI-M02 Human 73 pReceiver-M02 Expression-ready Non-viral Inquire
OC-GF008-M35 OC-HHI-M35 Human 73 pReceiver-M35 Expression-ready Non-viral Inquire
OC-GF008-M98 OC-HHI-M98 Human 73 pReceiver-M98 Expression-ready Non-viral Inquire
OC-GF008-Lv105 OC-HHI-Lv105 Human 73 pReceiver-Lv105 Expression-ready Lentiviral Inquire
OC-GF008-Lv242 OC-HHI-Lv242 Human 73 pReceiver-Lv242 Expression-ready Lentiviral Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.
Symbol Accession Species Description ORF length(bp) Product ID
H4C14 NM_003548.2 Human Homo sapiens histone cluster 2 H4 family member a (HIST2H4A), mRNA. 312 GC-B0019
H2AZ1 NM_002106.4 Human Homo sapiens H2A.Z variant histone 1 (H2AZ1), mRNA. 387 GC-B0023
H1-6 NM_005323.4 Human Homo sapiens H1.6 linker histone, cluster member (H1-6), mRNA. 624 GC-B0024
H1-1 NM_005325.4 Human Homo sapiens H1.1 linker histone, cluster member (H1-1), mRNA. 648 GC-B0032
H2AC11 NM_021064.5 Human Homo sapiens H2A clustered histone 11 (H2AC11), mRNA. 393 GC-B0053
H2AC19 NM_001040874.1 Human Homo sapiens histone cluster 2 H2A family member a4 (HIST2H2AA4), mRNA. 393 GC-B0054
H2AX NM_002105.3 Human Homo sapiens H2A.X variant histone (H2AX), mRNA. 432 GC-B0074
H1-2 NM_005319.4 Human Homo sapiens H1.2 linker histone, cluster member (H1-2), mRNA. 642 GC-B0101
H3C6 NM_003532.3 Human Homo sapiens H3 clustered histone 6 (H3C6), transcript variant 2, mRNA. 411 GC-B0108
H1-3 NM_005320.3 Human Homo sapiens H1.3 linker histone, cluster member (H1-3), mRNA. 666 GC-B0155
H1-4 NM_005321.3 Human Homo sapiens H1.4 linker histone, cluster member (H1-4), mRNA. 660 GC-B0156
H2AC8 NM_021052.4 Human Homo sapiens H2A clustered histone 8 (H2AC8), mRNA. 393 GC-B0157
H4C13 NM_003546.3 Human Homo sapiens H4 clustered histone 13 (H4C13), mRNA. 312 GC-B0163
H3C1 NM_003529.3 Human Homo sapiens H3 clustered histone 1 (H3C1), mRNA. 411 GC-B0165
H1-5 NM_005322.3 Human Homo sapiens H1.5 linker histone, cluster member (H1-5), mRNA. 681 GC-B0167
H3-4 NM_003493.3 Human Homo sapiens H3.4 histone (H3-4), mRNA. 411 GC-B0202
H3-3A NM_002107.7 Human Homo sapiens H3.3 histone A (H3-3A), transcript variant 1, mRNA. 411 GC-B0203
H4C8 NM_003543.4 Human Homo sapiens H4 clustered histone 8 (H4C8), mRNA. 312 GC-B0243
H2BC21 NM_003528.3 Human Homo sapiens H2B clustered histone 21 (H2BC21), mRNA. 381 GC-B0249
H1-0 NM_005318.4 Human Homo sapiens H1.0 linker histone (H1-0), mRNA. 585 GC-B0254
H2AC6 NM_003512.4 Human Homo sapiens H2A clustered histone 6 (H2AC6), mRNA. 393 GC-B0289
H4C12 NM_003541.3 Human Homo sapiens H4 clustered histone 12 (H4C12), mRNA. 312 GC-B0309
H1-8 NM_153833.3 Human Homo sapiens H1.8 linker histone (H1-8), transcript variant 1, mRNA. 1041 GC-E0590
H2AZ2 NM_012412.5 Human Homo sapiens H2A.Z variant histone 2 (H2AZ2), transcript variant 1, mRNA. 387 GC-I0220
H3C10 NM_003536.3 Human Homo sapiens H3 clustered histone 10 (H3C10), mRNA. 411 GC-S0288
H2BC12 NM_080593.2 Human Homo sapiens histone cluster 1 H2B family member k (HIST1H2BK), transcript variant 2, mRNA. 381 GC-T0456
H2BC14 NM_003521.3 Human Homo sapiens H2B clustered histone 14 (H2BC14), mRNA. 381 GC-T1039
H2BC9 NM_003524.3 Human Homo sapiens H2B clustered histone 9 (H2BC9), mRNA. 381 GC-T1040
H4C7 NM_003547.3 Human Homo sapiens H4 clustered histone 7 (H4C7), mRNA. 297 GC-T1041
H2AC14 NM_021066.3 Human Homo sapiens H2A clustered histone 14 (H2AC14), mRNA. 387 GC-T1265
H2BC13 NM_003519.4 Human Homo sapiens H2B clustered histone 13 (H2BC13), mRNA. 381 GC-T1835
H2BC15 NM_003520.4 Human Homo sapiens H2B clustered histone 15 (H2BC15), mRNA. 381 GC-T1836
H2AC7 NM_021065.3 Human Homo sapiens histone cluster 1 H2A family member d (HIST1H2AD), mRNA. 393 GC-T2068
H4C16 NM_175054.2 Human Homo sapiens histone cluster 4 H4 (HIST4H4), mRNA. 312 GC-T2234
H3C8 NM_003534.3 Human Homo sapiens H3 clustered histone 8 (H3C8), mRNA. 411 GC-T2285
H2BC4 NM_003526.3 Human Homo sapiens H2B clustered histone 4 (H2BC4), transcript variant 2, mRNA. 381 GC-T3213
H2AC12 NM_080596.3 Human Homo sapiens H2A clustered histone 12 (H2AC12), mRNA. 387 GC-T3215
H2AC16 NM_003511.3 Human Homo sapiens H2A clustered histone 16 (H2AC16), mRNA. 393 GC-T3216
H3C12 NM_003535.3 Human Homo sapiens H3 clustered histone 12 (H3C12), mRNA. 411 GC-T3219
H3C7 NM_021018.3 Human Homo sapiens H3 clustered histone 7 (H3C7), mRNA. 411 GC-T3220
H2AB3 NM_080720.3 Human Homo sapiens H2A.B variant histone 3 (H2AB3), mRNA. 348 GC-T4664
H2AC13 NM_003509.3 Human Homo sapiens H2A clustered histone 13 (H2AC13), mRNA. 393 GC-T7719
H3C4 NM_003530.4 Human Homo sapiens histone cluster 1 H3 family member d (HIST1H3D), mRNA. 411 GC-T7725
H4C9 NM_003495.3 Human Homo sapiens H4 clustered histone 9 (H4C9), mRNA. 312 GC-U0131
H3C11 NM_003533.3 Human Homo sapiens H3 clustered histone 11 (H3C11), mRNA. 411 GC-U0133
H4C6 NM_003540.4 Human Homo sapiens H4 clustered histone 6 (H4C6), mRNA. 312 GC-U0135
H2BC3 NM_021062.3 Human Homo sapiens H2B clustered histone 3 (H2BC3), mRNA. 381 GC-U1046
H2AC25 NM_033445.3 Human Homo sapiens H2A.W histone (H2AW), mRNA. 393 GC-V0232
H2AJ NM_177925.5 Human Homo sapiens H2A.J histone (H2AJ), transcript variant 1, mRNA. 390 GC-V0556
MACROH2A2 NM_018649.3 Human Homo sapiens macroH2A.2 histone (MACROH2A2), mRNA. 1119 GC-W0458

GPCRs

by | Mar 22, 2024 | Clone sets

Introduction

G protein-coupled receptors (GPCRs) are a large family of membrane protein receptors found only in eukaryotes. They are widely distributed in organs and tissues such as the central nervous system, immune system, cardiovascular system, and retina.
GPCRs that work under normal physiological conditions are mainly activated by ligand molecules and participate in the body’s development and normal functions. They are specific to multiple ligands, including GPR25, GPR35, TAS2R20, CRHR2, and OR6C74. However, if abnormal regulation of its related intracellular pathways occurs or exogenous pathogens attack body cells through them as receptors, it will lead to a series of diseases. Therefore, GPCRs are considered important drug development targets, with over 34% of modern drug targets being GPCRs.

Clone set information

Cat. No. Old Cat. No. Species Gene Vector Vector Type Price
OC-GF007-M02 OC-HGR-M02 Human 875 pReceiver-M02 Expression-ready Non-viral Inquire
OC-GF007-M35 OC-HGR-M35 Human 875 pReceiver-M35 Expression-ready Non-viral Inquire
OC-GF007-M98 OC-HGR-M98 Human 875 pReceiver-M98 Expression-ready Non-viral Inquire
OC-GF007-Lv105 OC-HGR-Lv105 Human 875 pReceiver-Lv105 Expression-ready Lentiviral Inquire
OC-GF007-Lv242 OC-HGR-Lv242 Human 875 pReceiver-Lv242 Expression-ready Lentiviral Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.
Symbol Accession Species Description ORF length(bp) Product ID
TACR1 NM_001058.4 Human Homo sapiens tachykinin receptor 1 (TACR1), transcript variant long, mRNA. 1224 GC-A0041
FPR2 NM_001462.3 Human Homo sapiens formyl peptide receptor 2 (FPR2), transcript variant 1, mRNA. 1056 GC-A0060
TACR3 NM_001059.3 Human Homo sapiens tachykinin receptor 3 (TACR3), mRNA. 1398 GC-A0068
CXCR2 NM_001557.4 Human Homo sapiens C-X-C motif chemokine receptor 2 (CXCR2), transcript variant 1, mRNA. 1083 GC-A0079
ADORA2B NM_000676.4 Human Homo sapiens adenosine A2b receptor (ADORA2B), mRNA. 999 GC-A0085
NPY NM_000905.4 Human Homo sapiens neuropeptide Y (NPY), mRNA. 294 GC-A0089
BRS3 NM_001727.2 Human Homo sapiens bombesin receptor subtype 3 (BRS3), mRNA. 1200 GC-A0093
MAS1 NM_002377.4 Human Homo sapiens MAS1 proto-oncogene, G protein-coupled receptor (MAS1), transcript variant 1, mRNA. 978 GC-A0099
GRPR NM_005314.3 Human Homo sapiens gastrin releasing peptide receptor (GRPR), mRNA. 1155 GC-A0132
NPY1R NM_000909.6 Human Homo sapiens neuropeptide Y receptor Y1 (NPY1R), mRNA. 1155 GC-A0167
ADRA2C NM_000683.4 Human Homo sapiens adrenoceptor alpha 2C (ADRA2C), mRNA. 1389 GC-A0187
GHRHR NM_000823.4 Human Homo sapiens growth hormone releasing hormone receptor (GHRHR), mRNA. 1272 GC-A0191
PTH1R NM_001184744.1 Human Homo sapiens parathyroid hormone 1 receptor (PTH1R), transcript variant 2, mRNA. 1782 GC-A0198
GPR183 NM_004951.5 Human Homo sapiens G protein-coupled receptor 183 (GPR183), mRNA. 1086 GC-A0214
CCKAR NM_000730.3 Human Homo sapiens cholecystokinin A receptor (CCKAR), mRNA. 1287 GC-A0232
EDNRB NM_001122659.2 Human Homo sapiens endothelin receptor type B (EDNRB), transcript variant 3, mRNA. 1329 GC-A0293
PTHLH NM_198964.2 Human Homo sapiens parathyroid hormone like hormone (PTHLH), transcript variant 3, mRNA. 528 GC-A0295
ADORA2A NM_001278499.2 Human Homo sapiens adenosine A2a receptor (ADORA2A), transcript variant 4, mRNA. 1239 GC-A0315
TMEM11 NM_003876.3 Human Homo sapiens transmembrane protein 11 (TMEM11), transcript variant 1, mRNA; nuclear gene for mitochondrial product. 579 GC-A0331
PTAFR NM_001164723.3 Human Homo sapiens platelet activating factor receptor (PTAFR), transcript variant 4, mRNA. 1029 GC-A0357
HTR1E NM_000865.3 Human Homo sapiens 5-hydroxytryptamine receptor 1E (HTR1E), mRNA. 1098 GC-A0398
CHRM3 NM_001347716.2 Human Homo sapiens cholinergic receptor muscarinic 3 (CHRM3), transcript variant 1, mRNA. 1773 GC-A0401
AVPR2 NM_000054.7 Human Homo sapiens arginine vasopressin receptor 2 (AVPR2), transcript variant 1, mRNA. 1116 GC-A0411
AGTR1 NM_000685.5 Human Homo sapiens angiotensin II receptor type 1 (AGTR1), transcript variant 1, mRNA. 1080 GC-A0417
CXCR4 NM_003467.3 Human Homo sapiens C-X-C motif chemokine receptor 4 (CXCR4), transcript variant 2, mRNA. 1059 GC-A0419
HTR1B NM_000863.3 Human Homo sapiens 5-hydroxytryptamine receptor 1B (HTR1B), mRNA. 1173 GC-A0434
HTR1D NM_000864.5 Human Homo sapiens 5-hydroxytryptamine receptor 1D (HTR1D), mRNA. 1134 GC-A0435
CHRM2 NM_001006630.2 Human Homo sapiens cholinergic receptor muscarinic 2 (CHRM2), transcript variant 1, mRNA. 1401 GC-A0448
GNRHR NM_000406.3 Human Homo sapiens gonadotropin releasing hormone receptor (GNRHR), transcript variant 1, mRNA. 987 GC-A0455
DRD1 NM_000794.5 Human Homo sapiens dopamine receptor D1 (DRD1), mRNA. 1341 GC-A0462
CNR2 NM_001841.3 Human Homo sapiens cannabinoid receptor 2 (CNR2), mRNA. 1083 GC-A0463
GRK6 NM_001004106.3 Human Homo sapiens G protein-coupled receptor kinase 6 (GRK6), transcript variant 1, mRNA. 1731 GC-A0473
GCGR NM_000160.5 Human Homo sapiens glucagon receptor (GCGR), mRNA. 1434 GC-A0475
PTGER1 NM_000955.3 Human Homo sapiens prostaglandin E receptor 1 (PTGER1), mRNA. 1209 GC-A0480
FPR3 NM_002030.5 Human Homo sapiens formyl peptide receptor 3 (FPR3), mRNA. 1062 GC-A0497
ADORA1 NM_001048230.2 Human Homo sapiens adenosine A1 receptor (ADORA1), transcript variant 2, mRNA. 981 GC-A0504
GLP1R NM_002062.5 Human Homo sapiens glucagon like peptide 1 receptor (GLP1R), transcript variant 1, mRNA. 1392 GC-A0510
TBXA2R NM_001060.6 Human Homo sapiens thromboxane A2 receptor (TBXA2R), transcript variant a, mRNA. 1032 GC-A0516
HTR2A NM_000621.5 Human Homo sapiens 5-hydroxytryptamine receptor 2A (HTR2A), transcript variant 1, mRNA. 1416 GC-A0533
AVPR1B NM_000707.5 Human Homo sapiens arginine vasopressin receptor 1B (AVPR1B), mRNA. 1275 GC-A0541
GPR176 NM_007223.3 Human Homo sapiens G protein-coupled receptor 176 (GPR176), transcript variant 1, mRNA. 1548 GC-A0542
HTR1F NM_001322210.2 Human Homo sapiens 5-hydroxytryptamine receptor 1F (HTR1F), transcript variant 3, mRNA. 1101 GC-A0549
NPR3 NM_000908.4 Human Homo sapiens natriuretic peptide receptor 3 (NPR3), transcript variant 2, mRNA. 1623 GC-A0569
GPR12 NM_005288.4 Human Homo sapiens G protein-coupled receptor 12 (GPR12), mRNA. 1005 GC-A0597
NTSR1 NM_002531.3 Human Homo sapiens neurotensin receptor 1 (NTSR1), mRNA. 1257 GC-A0601
PTGER2 NM_000956.4 Human Homo sapiens prostaglandin E receptor 2 (PTGER2), mRNA. 1077 GC-A0602
NPBWR1 NM_005285.5 Human Homo sapiens neuropeptides B and W receptor 1 (NPBWR1), mRNA. 987 GC-A0607
NPBWR2 NM_005286.4 Human Homo sapiens neuropeptides B and W receptor 2 (NPBWR2), mRNA. 1002 GC-A0608
PTH2R NM_005048.4 Human Homo sapiens parathyroid hormone 2 receptor (PTH2R), transcript variant 1, mRNA. 1653 GC-A0612
CCR3 NM_001837.4 Human Homo sapiens C-C motif chemokine receptor 3 (CCR3), transcript variant 1, mRNA. 1068 GC-A0619

Epigenetics

by | Mar 22, 2024 | Clone sets

Introduction

Epigenetics is the study of heritable changes in gene function that do not involve alterations to the DNA sequence. Such changes often involve alterations that affect gene expression regulation, including DNA methylation, histone modifications, chromosome remodeling, non-coding RNA regulation, gene silencing, nucleolar dominance, transposable element activation, and dosage compensation effects of sex-related genes.
Epigenetic regulation plays an important role in physiological processes such as development, aging, and immune regulation, as well as in the development of many diseases such as tumors, neurological disorders, and metabolic disorders. For example, epigenetic regulation of key genes related to neural development is an important regulatory mechanism that determines the differentiation of embryonic stem cells to neural cells.

Clone set information

Cat. No. Old Cat. No. Species Gene Vector Vector Type Price
OC-GF005-M02 OC-HEP-M02 Human 656 pReceiver-M02 Expression-ready Non-viral Inquire
OC-GF005-M35 OC-HEP-M35 Human 656 pReceiver-M35 Expression-ready Non-viral Inquire
OC-GF005-M98 OC-HEP-M98 Human 656 pReceiver-M98 Expression-ready Non-viral Inquire
OC-GF005-Lv105 OC-HEP-Lv105 Human 656 pReceiver-Lv105 Expression-ready Lentiviral Inquire
OC-GF005-Lv242 OC-HEP-Lv242 Human 656 pReceiver-Lv242 Expression-ready Lentiviral Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.
Symbol Accession Species Description ORF length(bp) Product ID
CDK2 NM_001798.5 Human Homo sapiens cyclin dependent kinase 2 (CDK2), transcript variant 1, mRNA. 897 GC-A0035
VDR NM_001017535.2 Human Homo sapiens vitamin D receptor (VDR), transcript variant 2, mRNA. 1284 GC-A0043
PRKCD NM_006254.4 Human Homo sapiens protein kinase C delta (PRKCD), transcript variant 1, mRNA. 2031 GC-A0211
ERBB4 NM_005235.3 Human Homo sapiens erb-b2 receptor tyrosine kinase 4 (ERBB4), transcript variant JM-a/CVT-1, mRNA. 3927 GC-A0212
YWHAB NM_139323.4 Human Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta (YWHAB), transcript variant 2, mRNA. 741 GC-A0340
CDK5 NM_004935.4 Human Homo sapiens cyclin dependent kinase 5 (CDK5), transcript variant 1, mRNA. 879 GC-A0348
CDK7 NM_001799.4 Human Homo sapiens cyclin dependent kinase 7 (CDK7), transcript variant 1, mRNA. 1041 GC-A0843
MAPKAPK3 NM_001243925.2 Human Homo sapiens MAPK activated protein kinase 3 (MAPKAPK3), transcript variant 2, mRNA. 1149 GC-A0888
LBR NM_002296.4 Human Homo sapiens lamin B receptor (LBR), transcript variant 1, mRNA. 1848 GC-A0933
CUL2 NM_001198778.2 Human Homo sapiens cullin 2 (CUL2), transcript variant 1, mRNA. 2295 GC-A1355
PRKCB NM_212535.3 Human Homo sapiens protein kinase C beta (PRKCB), transcript variant 1, mRNA. 2016 GC-A1601
PRMT1 NM_001207042.3 Human Homo sapiens protein arginine methyltransferase 1 (PRMT1), transcript variant 4, mRNA. 858 GC-A1680
PAK2 NM_002577.4 Human Homo sapiens p21 (RAC1) activated kinase 2 (PAK2), mRNA. 1575 GC-A1683
TAF6 NM_001190415.2 Human Homo sapiens TATA-box binding protein associated factor 6 (TAF6), transcript variant 5, mRNA. 2145 GC-A1699
SMARCD1 NM_003076.5 Human Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 (SMARCD1), transcript variant 1, mRNA. 1548 GC-A1760
PRKAG1 NM_001206710.2 Human Homo sapiens protein kinase AMP-activated non-catalytic subunit gamma 1 (PRKAG1), transcript variant 4, mRNA. 900 GC-A2011
TP53 NM_001276760.3 Human Homo sapiens tumor protein p53 (TP53), transcript variant 1, mRNA. 1065 GC-A2030
AURKB NM_001313951.1 Human Homo sapiens aurora kinase B (AURKB), transcript variant 5, mRNA. 912 GC-A2150
CUL2 NM_003591.4 Human Homo sapiens cullin 2 (CUL2), transcript variant 3, mRNA. 2238 GC-A2162
DNMT3B NM_001207055.2 Human Homo sapiens DNA methyltransferase 3 beta (DNMT3B), transcript variant 7, mRNA. 2187 GC-A2214
DNMT3B NM_001207056.2 Human Homo sapiens DNA methyltransferase 3 beta (DNMT3B), transcript variant 8, mRNA. 2085 GC-A2215
CHEK1 NM_001244846.1 Human Homo sapiens checkpoint kinase 1 (CHEK1), transcript variant 4, mRNA. 1329 GC-A2388
ATF2 NM_001256091.2 Human Homo sapiens activating transcription factor 2 (ATF2), transcript variant 3, mRNA. 1464 GC-A2490
ATF2 NM_001256094.2 Human Homo sapiens activating transcription factor 2 (ATF2), transcript variant 6, mRNA. 630 GC-A2492
APBB1 NM_001257320.2 Human Homo sapiens amyloid beta precursor protein binding family B member 1 (APBB1), transcript variant 6, mRNA. 1356 GC-A2619
SUPT3H NM_001261823.2 Human Homo sapiens SPT3 homolog, SAGA and STAGA complex component (SUPT3H), transcript variant 3, mRNA. 498 GC-A2725
JARID2 NM_001267040.1 Human Homo sapiens jumonji and AT-rich interaction domain containing 2 (JARID2), transcript variant 2, mRNA. 3225 GC-A2742
EZH2 NM_001203247.2 Human Homo sapiens enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2), transcript variant 3, mRNA. 2241 GC-A2944
MTA1 NM_004689.3 Human Homo sapiens metastasis associated 1 (MTA1), transcript variant 1, mRNA. 2148 GC-A2952
MAX NM_145113.3 Human Homo sapiens MYC associated factor X (MAX), transcript variant 3, mRNA. 312 GC-A2960
CENPC NM_001812.4 Human Homo sapiens centromere protein C (CENPC), transcript variant 1, mRNA. 2832 GC-A3021
TP53 NM_001276697.3 Human Homo sapiens tumor protein p53 (TP53), transcript variant 5, mRNA. 705 GC-A3114
TOP2B NM_001068.3 Human Homo sapiens topoisomerase (DNA) II beta (TOP2B), transcript variant 2, mRNA. 4866 GC-A3120
AURKB NM_001313950.2 Human Homo sapiens aurora kinase B (AURKB), transcript variant 4, mRNA. 1035 GC-A3181
HIRIP3 NM_003609.5 Human Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 1, mRNA. 1671 GC-A3187
REST NM_005612.5 Human Homo sapiens RE1 silencing transcription factor (REST), transcript variant 1, mRNA. 3294 GC-A3251
NPAS2 NM_002518.4 Human Homo sapiens neuronal PAS domain protein 2 (NPAS2), mRNA. 2475 GC-A3302
BRPF1 NM_004634.3 Human Homo sapiens bromodomain and PHD finger containing 1 (BRPF1), transcript variant 2, mRNA. 3645 GC-A3584
KDM6A NM_021140.4 Human Homo sapiens lysine demethylase 6A (KDM6A), transcript variant 3, mRNA. 4206 GC-A3666
SMARCB1 NM_003073.5 Human Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 (SMARCB1), transcript variant 1, mRNA. 1158 GC-A3765
RBBP5 NM_005057.4 Human Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 1, mRNA. 1617 GC-A3799
APOBEC1 NM_001644.5 Human Homo sapiens apolipoprotein B mRNA editing enzyme catalytic subunit 1 (APOBEC1), transcript variant 1, mRNA. 711 GC-A4151
CUL1 NM_003592.3 Human Homo sapiens cullin 1 (CUL1), transcript variant 1, mRNA. 2331 GC-A4270
PRKAB1 NM_006253.5 Human Homo sapiens protein kinase AMP-activated non-catalytic subunit beta 1 (PRKAB1), mRNA. 813 GC-A4283
E2F6 NM_212540.3 Human Homo sapiens E2F transcription factor 6 (E2F6), transcript variant f, mRNA. 390 GC-A4388
ERCC6 NM_001346440.2 Human Homo sapiens ERCC excision repair 6, chromatin remodeling factor (ERCC6), transcript variant 4, mRNA. 4482 GC-A4394
CDC6 NM_001254.4 Human Homo sapiens cell division cycle 6 (CDC6), mRNA. 1683 GC-A4506
E2F6 NM_001278277.2 Human Homo sapiens E2F transcription factor 6 (E2F6), transcript variant d, mRNA. 621 GC-A4578
DPF3 NM_001280542.3 Human Homo sapiens double PHD fingers 3 (DPF3), transcript variant 2, mRNA. 1137 GC-A4747
UBE2A NM_001282161.2 Human Homo sapiens ubiquitin conjugating enzyme E2 A (UBE2A), transcript variant 4, mRNA. 360 GC-A4851