Validated All-in-One™ qPCR Primer for CD27(NM_001242.5) [Search again]

Catalog#: HQP127571(click here to view gene annotation page)
Symbol: CD27
Species: Human
Target Gene Accession: NM_001242.5
Alias: S152, S152. LPFS2, T14, TNFRSF7, Tp55
Gene Description: CD27 molecule
Estimated Delivery: 1-3 weeks, but may vary. Please email sales@genecopoeia.com  to confirm ETA.
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Important Note: By default, qPCR primer pairs are designed to measure the expression level of the splice variant (accession number) you selected for this gene WITHOUT consideration of other possible variants of this gene. If this gene has multiple variants, and you would like to measure the expression levels of one particular variant, multiple variants, or all variants, please contact us for a custom service project at inquiry@genecopoeia.com.


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HQP127571 All-in-One™ qPCR Primer for NM_001242.5 (200 reactions) CD27 inquire
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Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq].


Gene References into function