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MitoBeacon™ Red

Introduction

MitoBeacon™ Red (Known as MitoTracker® Red CMXRos, Trade Mark of Molecular Probes) is an red-fluorescent dye that stains mitochondria in live cells and its accumulation is dependent upon membrane potential. The dye is well-retained after aldehyde fixation. This dye is provided as 1 mg/mL solution in DMSO.

Specifications:     
Excitation/Emission: 580/600 nm
Shipping Condition: Ambient
Storage Conditions: -20ºC, protect from light
Molecular Formula: C32H32Cl2N2O
Molecular Weight: 531.52
CAS Number: 167095-09-2  

 

To Order

Buy Cat.No. Product name Ex/Em(nm) Size Price
C042 MitoBeacon™ Red 580/600 1 ml $120

Protocol
MSDS
COA

Documents

Protocol (PDF): C042
MSDS (PDF):  MSDS-C042
COA (PDF):  C042

Reference:

Dysfunctions of cellular oxidative metabolism in patients with mutations in the NDUFS1 and NDUFS4 genes of complex I.
Iuso A, Scacco S, Piccoli C, Bellomo F, Petruzzella V, Trentadue R, Minuto M, Ripoli M, Capitanio N, Zeviani M, Papa S
J Biol Chem (2006) 281:10374-10380

Control of mitochondrial structure and function by the Yorkie/YAP oncogenic pathway.
Nagaraj R, Gururaja-Rao S, Jones KT, Slattery M, Negre N, Braas D, Christofk H, White KP, Mann R, Banerjee U,
Genes Dev (2012) 26:2027-2037
Product usage: Proliferation, DNA Synthesis, Click-iT EdU, Imaging, in vivo

Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes.
Zhao T, Huang X, Han L, Wang X, Cheng H, Zhao Y, Chen Q, Chen J, Cheng H, Xiao R, Zheng M,
J Biol Chem (2012) 287:23615-23625
Product usage: Lysotracker, ER-Tracker, Mitotracker, Autophagy, Imaging

Frequently asked questions (FAQs)

It looks like my MitoBeacon™ dye is staining more than just the mitochondria. Why?
This is typically a result of using too high of a concentration of the MitoBeacon™ dye. Most organic dyes are used in the low micromolar range. The MitoBeacon™ dyes are used at a much lower concentration, around 50–200 nanomolar. Higher concentrations can cause background fluorescence and non-mitochondrial staining.