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MitoBeacon™ Orange

Introduction

MitoBeacon™ Orange (Known as MitoTracker® Orange CMTMRos, Trade Mark of Molecular Probes) is an orange-fluorescent dye that stains mitochondria in live cells and its accumulation is dependent upon membrane potential. The dye is well-retained after aldehyde fixation. This dye is provided as 1 mg/mL solution in DMSO.

Specifications:     
Excitation/Emission: 554/575 nm
Shipping Condition: Ambient
Storage Conditions: -20ºC, protect from light
Molecular Formula: C24H24Cl2N2O
Molecular Weight: 427.37
CAS Number: N/A  

 

To Order

Buy Cat.No. Product name Ex/Em(nm) Size Price
C041 MitoBeacon™ Orange 554/575 1 ml $120

Protocol
MSDS
COA

Documents

Protocol (PDF): C041
MSDS (PDF):  MSDS-C041
COA (PDF):  C041

Reference

Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes.
Shim SH, Xia C, Zhong G, Babcock HP, Vaughan JC, Huang B, Wang X, Xu C, Bi GQ, Zhuang X,
Proc Natl Acad Sci U S A (2012) 109:13978-13983

SM-20 is a novel mitochondrial protein that causes caspase-dependent cell death in nerve growth factor-dependent neurons.
Lipscomb EA, Sarmiere PD, Freeman RS
J Biol Chem (2001) 276:5085-5092

Frequently asked questions (FAQs)

It looks like my MitoBeacon™ dye is staining more than just the mitochondria. Why?
This is typically a result of using too high of a concentration of the MitoBeacon dye. Most organic dyes are used in the low micromolar range. The MitoBeacon dyes are used at a much lower concentration, around 50–200 nanomolar. Higher concentrations can cause background fluorescence and non-mitochondrial staining.