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LysoBeacon™ Green

Introduction

LysoBeacon™ Green (Known as LysoSensor™ Green DND-189, Trade Mark of Molecular Probes) is a green lysosomal dye that stains lysosome in living cells.LysoBeacon Green can be used to measure the pH of acidic organelles, such as lysosomes. The LysoBeacon Green becomes more fluorescent in acidic environments with pKa at ~5.2. This dye is provided as 1 mg/mL solution in DMSO.

Specifications:     
Excitation/Emission: 443/505 nm
Shipping Condition: Ambient
Storage Conditions: -20ºC, protect from light
Molecular Formula: C24H22N4O2
Molecular Weight: 398.46
CAS Number: N/A  

 

To Order

Buy Cat.No. Product name Ex/Em(nm) Size Price
C048 LysoBeacon™ Green 443/505 1 ml $100

Protocol
MSDS
COA

Documents

Protocol (PDF): C048
MSDS (PDF):  MSDS-C048
COA (PDF):  C048

Reference

Functional dissection of COP-I subunits in the biogenesis of multivesicular endosomes.
Gu F, Aniento F, Parton RG, Gruenberg J
J Cell Biol (1997) 139:1183-1195

Fluorescent indicators for intracellular pH.
Han J, Burgess K,
Chem Rev (2010) 110:2709-2728
Product usage: Review of the structure and properties of fluorescent pH indicators.

Endocytic Trafficking of Cholera Toxin in Balb 3T3 Cells
Blagojevic G, Mahmutefendic H, Kucic N, Tomas MI, Lucin P
Croatica Chemica Acta (2008) 81:191-202