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Caspase-3/7 Inhibitor Ac-DEVD-CHO

Introduction

Ac-DEVD-CHO is a synthetic tetrapeptide competitive inhibitor for caspase-3/7. It contains the amino acid sequence of the PARP cleavage site. Ac-DEVD-CHO can be used to inhibitor caspase-3/7 activity in apoptotic cells, and to study events downstream of caspase-3/7 activation.

 

Substrate Specifications

Substrate name: Ac-DEVD-CHO
Molecular weight: 502.5
Peptide sequence: DEVD
Useful to inhibit: Caspase-3, -7
Storage Condition: -20 oC
Shipping Condition: Room temperature

Applications

Enzyme assay.