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E3 ubiquitin ligases

Introduction

E3 ubiquitin ligases are key components of the ubiquitin–proteasome system, selecting and tagging target proteins for degradation or regulation. With over 600 members, they control vital processes such as cell cycle, DNA repair, and immune signaling. Dysregulated E3 activity drives cancer, neurodegeneration, and inflammation, making E3s important targets for mechanistic studies and drug development. Genecopoeia offers E3 Related Gene qPCR Array for mechanistic studies and drug development.

qPCR Array information

Cat. no.	Product name	Species	Gene	Number of plates	Price
QG100	Exprofile™ Human E3 Ubiquitin Ligases Related Gene qPCR Array	Human	607	8 x 96-well	Inquire

qPCR Array list

For array list please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.

Symbol	Accession	Species	Description	Product ID
HUWE1	NM_031407.6	Human	Homo sapiens HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 (HUWE1), mRNA.	HQP000096
TRIM28	NM_005762.2	Human	Homo sapiens tripartite motif containing 28 (TRIM28), mRNA.	HQP000197
STUB1	NM_005861.3	Human	Homo sapiens STIP1 homology and U-box containing protein 1 (STUB1), transcript variant 1, mRNA.	HQP000334
KLHL41	NM_006063.2	Human	Homo sapiens kelch like family member 41 (KLHL41), mRNA.	HQP000400
TRIM22	NM_006074.4	Human	Homo sapiens tripartite motif containing 22 (TRIM22), transcript variant 1, mRNA.	HQP000423
TRIM38	NM_006355.4	Human	Homo sapiens tripartite motif containing 38 (TRIM38), mRNA.	HQP000574
RCBTB2	NM_001268.3	Human	Homo sapiens RCC1 and BTB domain containing protein 2 (RCBTB2), transcript variant 2, mRNA.	HQP001169
WWP1	NM_007013.3	Human	Homo sapiens WW domain containing E3 ubiquitin protein ligase 1 (WWP1), mRNA.	HQP001203
TRIM31	NM_007028.4	Human	Homo sapiens tripartite motif containing 31 (TRIM31), transcript variant 1, mRNA.	HQP001229
FBXO32	NM_058229.3	Human	Homo sapiens F-box protein 32 (FBXO32), transcript variant 1, mRNA.	HQP001749
MARCHF3	NM_178450.4	Human	Homo sapiens membrane associated ring-CH-type finger 3 (MARCHF3), mRNA.	HQP001775
RNF32	NM_030936.3	Human	Homo sapiens ring finger protein 32 (RNF32), transcript variant 3, mRNA.	HQP003014
DCST1	NM_152494.3	Human	Homo sapiens DC-STAMP domain containing 1 (DCST1), transcript variant 1, mRNA.	HQP003487
DTX3L	NM_138287.2	Human	Homo sapiens deltex E3 ubiquitin ligase 3L (DTX3L), mRNA.	HQP003638
RNF217	NM_152553.4	Human	Homo sapiens ring finger protein 217 (RNF217), transcript variant 2, mRNA.	HQP003766
OTUD7A	NM_130901.2	Human	Homo sapiens OTU domain containing 7A (OTUD7A), mRNA. Codon-optimized for Homo sapiens.	HQP003993
MARCHF10	NM_152598.3	Human	Homo sapiens membrane associated ring-CH-type finger 10 (MARCHF10), transcript variant 1, mRNA.	HQP004014
DDB1	NM_001923.4	Human	Homo sapiens damage specific DNA binding protein 1 (DDB1), mRNA.	HQP004111
KCNG3	NM_133329.5	Human	Homo sapiens potassium voltage-gated channel modifier subfamily G member 3 (KCNG3), transcript variant 1, mRNA.	HQP004278
DTX1	NM_004416.2	Human	Homo sapiens deltex E3 ubiquitin ligase 1 (DTX1), mRNA.	HQP004495
DTX3	NM_178502.3	Human	Homo sapiens deltex homolog 3 (Drosophila) (DTX3), mRNA.	HQP004627
UBR1	NM_174916.2	Human	Homo sapiens ubiquitin protein ligase E3 component n-recognin 1 (UBR1), mRNA.	HQP004660
FBXO15	NM_152676.2	Human	Homo sapiens F-box protein 15 (FBXO15), transcript variant 1, mRNA.	HQP004821
RNF152	NM_173557.2	Human	Homo sapiens ring finger protein 152 (RNF152), mRNA.	HQP005226
FBXL13	NM_145032.3	Human	Homo sapiens F-box and leucine rich repeat protein 13 (FBXL13), transcript variant 1, mRNA.	HQP005353
LNX2	NM_153371.3	Human	Homo sapiens ligand of numb-protein X 2 (LNX2), mRNA.	HQP005359
ZNRF2	NM_147128.3	Human	Homo sapiens zinc and ring finger 2 (ZNRF2), mRNA.	HQP005384
RHOBTB3	NM_014899.3	Human	Homo sapiens Rho related BTB domain containing 3 (RHOBTB3), mRNA.	HQP005489
KDM2A	NM_012308.2	Human	Homo sapiens lysine demethylase 2A (KDM2A), transcript variant 1, mRNA.	HQP005645
FBXO21	NM_033624.2	Human	Homo sapiens F-box protein 21 (FBXO21), transcript variant 1, mRNA.	HQP005668
HECW1	NM_015052.4	Human	Homo sapiens HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 (HECW1), mRNA.	HQP005726
MYCBP2	NM_015057.4	Human	Homo sapiens MYC binding protein 2 (MYCBP2), mRNA.	HQP005731
TRIM35	NM_171982.4	Human	Homo sapiens tripartite motif containing 35 (TRIM35), transcript variant 1, mRNA.	HQP005744
CUL9	NM_015089.3	Human	Homo sapiens cullin 9 (CUL9), mRNA.	HQP005770
FBXW11	NM_012300.2	Human	Homo sapiens F-box and WD repeat domain containing 11 (FBXW11), transcript variant 3, mRNA.	HQP005960
MGRN1	NM_015246.3	Human	Homo sapiens mahogunin ring finger 1 (MGRN1), transcript variant 1, mRNA.	HQP005965
NEDD4L	NM_015277.5	Human	Homo sapiens neural precursor cell expressed, developmentally down-regulated 4-like (NEDD4L), transcript variant d, mRNA.	HQP005996
KCTD2	NM_015353.2	Human	Homo sapiens potassium channel tetramerization domain containing 2 (KCTD2), transcript variant 1, mRNA.	HQP006160
RPL13A	NM_012423.4	Human	Homo sapiens ribosomal protein L13a (RPL13A), transcript variant 1, mRNA.	HQP006171
PATZ1	NM_014323.2	Human	Homo sapiens POZ/BTB and AT hook containing zinc finger 1 (PATZ1), transcript variant 1, mRNA.	HQP006256
MKRN2	NM_014160.4	Human	Homo sapiens makorin ring finger protein 2 (MKRN2), transcript variant 1, mRNA.	HQP006268
ZBTB38	NM_001080412.2	Human	Homo sapiens zinc finger and BTB domain containing 38 (ZBTB38), transcript variant 1, mRNA.	HQP006483
SHPRH	NM_001042683.2	Human	Homo sapiens SNF2 histone linker PHD RING helicase (SHPRH), transcript variant 1, mRNA.	HQP006687
FBXO7	NM_012179.3	Human	Homo sapiens F-box protein 7 (FBXO7), transcript variant 1, mRNA.	HQP006722
ARIH1	NM_005744.3	Human	Homo sapiens ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) (ARIH1), mRNA.	HQP006752
FBXW2	NM_012164.3	Human	Homo sapiens F-box and WD repeat domain containing 2 (FBXW2), transcript variant 1, mRNA.	HQP007112
FBXO2	NM_012168.5	Human	Homo sapiens F-box protein 2 (FBXO2), mRNA.	HQP007137
FBXO10	NM_012166.2	Human	Homo sapiens F-box protein 10 (FBXO10), mRNA.	HQP007178
FBXO9	NM_012347.4	Human	Homo sapiens F-box protein 9 (FBXO9), transcript variant 1, mRNA.	HQP007179
FBXO8	NM_012180.2	Human	Homo sapiens F-box protein 8 (FBXO8), mRNA.	HQP007182