All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

Kinases

Introduction

Kinases are enzymes that catalyze the transfer of phosphate groups from high-energy phosphorus-containing molecules (e.g., ATP) to a substrate, and the largest kinase group is protein kinases. Kinases exert their effects by phosphorylating their respective downstream specific substrate proteins. They catalyze the transfer of γ-phosphate from ATP or GTP to the hydroxyl groups of serine, threonine, and tyrosine in substrate proteins or the glycosyl portion of lipids.

Kinases include: adenylate kinase (AMPK), creatine kinase (CK), pyruvate kinase (PK), hexokinase (HK), nucleoside diphosphate kinases (NDPKs), and thymidine kinases (TK1/TK2). Kinase dysregulation can lead to changes in enzyme activity and/or enzyme expression, subcellular localization, kinase stability, protein-protein interactions, etc. Aberrant regulation of kinase-mediated signaling pathways is responsible for all major human pathological conditions, such as cancer, cardiovascular diseases, neurodegenerative diseases, and metabolic disorders.

Clone set information

Cat. No.	Old Cat. No.	Species	Gene	Vector	Vector Type	Price
OC-GF013-M02	OC-HKI-M02	Human	666	pReceiver-M02	Expression-ready Non-viral	Inquire
OC-GF013-M35	OC-HKI-M35	Human	666	pReceiver-M35	Expression-ready Non-viral	Inquire
OC-GF013-M98	OC-HKI-M98	Human	666	pReceiver-M98	Expression-ready Non-viral	Inquire
OC-GF013-Lv105	OC-HKI-Lv105	Human	666	pReceiver-Lv105	Expression-ready Lentiviral	Inquire
OC-GF013-Lv242	OC-HKI-Lv242	Human	666	pReceiver-Lv242	Expression-ready Lentiviral	Inquire
OC-GF013-GC	OC-HKI-GC	Human	666	pDONR™ Vector	Gateway shuttle	Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.

Symbol	Accession	Species	Description	ORF length(bp)	Product ID
CDKN1A	NM_001220778.2	Human	Homo sapiens cyclin dependent kinase inhibitor 1A (CDKN1A), transcript variant 4, mRNA.	495	GC-G0313
ABL2	NM_005158.5	Human	Homo sapiens ABL proto-oncogene 2, non-receptor tyrosine kinase (ABL2), transcript variant c, mRNA.	3504	GC-Z1255
CPNE3	NM_003909.5	Human	Homo sapiens copine 3 (CPNE3), mRNA.	1614	GC-S0040
PACSIN1	NM_001199583.3	Human	Homo sapiens protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 2, mRNA.	1335	GC-T4656
STK40	NM_032017.3	Human	Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 3, mRNA.	1308	GC-T8395
NEK3	NM_002498.3	Human	Homo sapiens NIMA related kinase 3 (NEK3), transcript variant 1, mRNA.	1521	GC-T8423
MAPKAP1	NM_024117.4	Human	Homo sapiens MAPK associated protein 1 (MAPKAP1), transcript variant 2, mRNA.	1461	GC-V0508
CAMK1D	NM_153498.4	Human	Homo sapiens calcium/calmodulin dependent protein kinase ID (CAMK1D), transcript variant 2, mRNA.	1158	GC-Y2805
AKT1	NM_005163.2	Human	Homo sapiens AKT serine/threonine kinase 1 (AKT1), transcript variant 1, mRNA.	1443	GC-A0022
CDK2	NM_001798.5	Human	Homo sapiens cyclin dependent kinase 2 (CDK2), transcript variant 1, mRNA.	897	GC-A0035
EPHA3	NM_005233.6	Human	Homo sapiens EPH receptor A3 (EPHA3), transcript variant 1, mRNA.	2952	GC-A0059
TGFBR2	NM_003242.6	Human	Homo sapiens transforming growth factor beta receptor 2 (TGFBR2), transcript variant 2, mRNA.	1704	GC-A0063
ACVR2A	NM_001616.5	Human	Homo sapiens activin A receptor type 2A (ACVR2A), transcript variant 2, mRNA.	1542	GC-A0075
EPHA2	NM_004431.5	Human	Homo sapiens EPH receptor A2 (EPHA2), transcript variant 1, mRNA.	2931	GC-A0125
MAPK3	NM_002746.3	Human	Homo sapiens mitogen-activated protein kinase 3 (MAPK3), transcript variant 1, mRNA.	1140	GC-A0161
FGFR4	NM_213647.3	Human	Homo sapiens fibroblast growth factor receptor 4 (FGFR4), transcript variant 3, mRNA.	2409	GC-A0196
RPS6KA1	NM_002953.3	Human	Homo sapiens ribosomal protein S6 kinase A1 (RPS6KA1), transcript variant 1, mRNA.	2208	GC-A0206
PRKCD	NM_006254.4	Human	Homo sapiens protein kinase C delta (PRKCD), transcript variant 1, mRNA.	2031	GC-A0211
ERBB4	NM_005235.3	Human	Homo sapiens erb-b2 receptor tyrosine kinase 4 (ERBB4), transcript variant JM-a/CVT-1, mRNA.	3927	GC-A0212
ITK	NM_005546.4	Human	Homo sapiens IL2 inducible T cell kinase (ITK), mRNA.	1863	GC-A0222
GRK5	NM_005308.3	Human	Homo sapiens G protein-coupled receptor kinase 5 (GRK5), mRNA.	1773	GC-A0230
CAMK4	NM_001744.4	Human	Homo sapiens calcium/calmodulin-dependent protein kinase IV (CAMK4), mRNA.	1422	GC-A0231
DDR1	NM_013993.3	Human	Homo sapiens discoidin domain receptor tyrosine kinase 1 (DDR1), transcript variant 2, mRNA.	2742	GC-A0234
PSKH1	NM_006742.3	Human	Homo sapiens protein serine kinase H1 (PSKH1), mRNA.	1275	GC-A0235
PRKACB	NM_002731.4	Human	Homo sapiens protein kinase cAMP-activated catalytic subunit beta (PRKACB), transcript variant 2, mRNA.	1056	GC-A0258
FGFR1	NM_023106.3	Human	Homo sapiens fibroblast growth factor receptor 1 (FGFR1), transcript variant 4, mRNA.	2196	GC-A0260
EIF2AK2	NM_002759.4	Human	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 1, mRNA.	1656	GC-A0265
GRK2	NM_001619.5	Human	Homo sapiens G protein-coupled receptor kinase 2 (GRK2), mRNA.	2070	GC-A0311
PRKACA	NM_002730.4	Human	Homo sapiens protein kinase cAMP-activated catalytic subunit alpha (PRKACA), transcript variant 1, mRNA.	1056	GC-A0326
CDK16	NM_006201.5	Human	Homo sapiens cyclin dependent kinase 16 (CDK16), transcript variant 1, mRNA.	1491	GC-A0347
CDK5	NM_004935.4	Human	Homo sapiens cyclin dependent kinase 5 (CDK5), transcript variant 1, mRNA.	879	GC-A0348
TGFA	NM_001099691.3	Human	Homo sapiens transforming growth factor alpha (TGFA), transcript variant 2, mRNA.	480	GC-A0352
MAPK1	NM_002745.5	Human	Homo sapiens mitogen-activated protein kinase 1 (MAPK1), transcript variant 1, mRNA.	1083	GC-A0354
FER	NM_005246.4	Human	Homo sapiens FER tyrosine kinase (FER), transcript variant 1, mRNA.	2469	GC-A0374
PRKCH	NM_006255.5	Human	Homo sapiens protein kinase C eta (PRKCH), mRNA.	2052	GC-A0394
PRKG1	NM_006258.4	Human	Homo sapiens protein kinase cGMP-dependent 1 (PRKG1), transcript variant 2, mRNA.	2061	GC-A0409
GRK6	NM_001004106.3	Human	Homo sapiens G protein-coupled receptor kinase 6 (GRK6), transcript variant 1, mRNA.	1731	GC-A0473
FYN	NM_002037.5	Human	Homo sapiens FYN proto-oncogene, Src family tyrosine kinase (FYN), transcript variant 1, mRNA.	1614	GC-A0485
ROR1	NM_005012.4	Human	Homo sapiens receptor tyrosine kinase like orphan receptor 1 (ROR1), transcript variant 1, mRNA.	2814	GC-A0499
FRK	NM_002031.3	Human	Homo sapiens fyn related Src family tyrosine kinase (FRK), mRNA.	1518	GC-A0509
KIT	NM_000222.3	Human	Homo sapiens KIT proto-oncogene, receptor tyrosine kinase (KIT), transcript variant 1, mRNA.	2931	GC-A0519
PRKAR2A	NM_004157.4	Human	Homo sapiens protein kinase cAMP-dependent type II regulatory subunit alpha (PRKAR2A), transcript variant 1, mRNA.	1215	GC-A0524
BTK	NM_000061.3	Human	Homo sapiens Bruton tyrosine kinase (BTK), transcript variant 1, mRNA.	1980	GC-A0534
CAMK1	NM_003656.5	Human	Homo sapiens calcium/calmodulin dependent protein kinase I (CAMK1), mRNA.	1113	GC-A0562
NEK2	NM_002497.4	Human	Homo sapiens NIMA related kinase 2 (NEK2), transcript variant 1, mRNA.	1338	GC-A0662
MAP2K4	NM_003010.4	Human	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant 1, mRNA.	1200	GC-A0727
BLK	NM_001715.3	Human	Homo sapiens BLK proto-oncogene, Src family tyrosine kinase (BLK), transcript variant 1, mRNA.	1518	GC-A0751
STK38	NM_001305102.2	Human	Homo sapiens serine/threonine kinase 38 (STK38), transcript variant 2, mRNA.	1398	GC-A0772
MAP2K1	NM_002755.4	Human	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), mRNA.	1182	GC-A0826
CAMK2G	NM_172170.5	Human	Homo sapiens calcium/calmodulin dependent protein kinase II gamma (CAMK2G), transcript variant 3, mRNA.	1557	GC-A0838