Epigenetics

Introduction

Epigenetics is the study of heritable changes in gene function that do not involve alterations to the DNA sequence. Such changes often involve alterations that affect gene expression regulation, including DNA methylation, histone modifications, chromosome remodeling, non-coding RNA regulation, gene silencing, nucleolar dominance, transposable element activation, and dosage compensation effects of sex-related genes.
Epigenetic regulation plays an important role in physiological processes such as development, aging, and immune regulation, as well as in the development of many diseases such as tumors, neurological disorders, and metabolic disorders. For example, epigenetic regulation of key genes related to neural development is an important regulatory mechanism that determines the differentiation of embryonic stem cells to neural cells.

Clone set information

Cat. No. Old Cat. No. Species Gene Vector Vector Type Price
OC-GF005-M02 OC-HEP-M02 Human 656 pReceiver-M02 Expression-ready Non-viral Inquire
OC-GF005-M35 OC-HEP-M35 Human 656 pReceiver-M35 Expression-ready Non-viral Inquire
OC-GF005-M98 OC-HEP-M98 Human 656 pReceiver-M98 Expression-ready Non-viral Inquire
OC-GF005-Lv105 OC-HEP-Lv105 Human 656 pReceiver-Lv105 Expression-ready Lentiviral Inquire
OC-GF005-Lv242 OC-HEP-Lv242 Human 656 pReceiver-Lv242 Expression-ready Lentiviral Inquire
OC-GF005-GC OC-HEP-GC Human 656 pDONR™ Vector Gateway shuttle Inquire

Clone list

The form only shows 50 clones of the whole set. Please contact us at 1-301-762-0888 or inquiry@genecopoeia.com if you have any questions.
Symbol Accession Species Description ORF length(bp) Product ID
TAL1 NM_003189.2 Human Homo sapiens T-cell acute lymphocytic leukemia 1 (TAL1), mRNA. 996 GC-Z7474
CUL5 NM_003478.6 Human Homo sapiens cullin 5 (CUL5), mRNA. 2343 GC-E1912
AKT1 NM_001014431.2 Human Homo sapiens AKT serine/threonine kinase 1 (AKT1), transcript variant 3, mRNA. 1443 GC-Z5980
GRB7 NM_001030002.3 Human Homo sapiens growth factor receptor bound protein 7 (GRB7), transcript variant 2, mRNA. 1599 GC-H3387
PRNP NM_000311.5 Human Homo sapiens prion protein (PRNP), transcript variant 1, mRNA. 762 GC-I2265
IHH NM_002181.3.01 Human Homo sapiens indian hedgehog (IHH), mRNA. Codon-optimized for Homo sapiens. 1236 GC-X1015
FAS NM_000043.6 Human Homo sapiens Fas cell surface death receptor (FAS), transcript variant 1, mRNA. 1008 GC-G0198
DDB2 NM_000107.3 Human Homo sapiens damage specific DNA binding protein 2 (DDB2), transcript variant WT, mRNA. 1284 GC-S0502
TAFAZZIN NM_000116.5 Human Homo sapiens tafazzin, phospholipid-lysophospholipid transacylase (TAFAZZIN), transcript variant 1, mRNA. 879 GC-U0071
ENG NM_000118.4 Human Homo sapiens endoglin (ENG), transcript variant 2, mRNA. 1878 GC-Y2005
FSHR NM_000145.4 Human Homo sapiens follicle stimulating hormone receptor (FSHR), transcript variant 1, mRNA. 2088 GC-Z8876
G6PC1 NM_000151.4 Human Homo sapiens glucose-6-phosphatase catalytic subunit 1 (G6PC1), transcript variant 1, mRNA. 1074 GC-C0592
GLI3 NM_000168.6 Human Homo sapiens GLI family zinc finger 3 (GLI3), mRNA. 4743 GC-A4397
MSH6 NM_000179.3 Human Homo sapiens mutS homolog 6 (MSH6), transcript variant 1, mRNA. 4083 GC-M0422
SHH NM_000193.4 Human Homo sapiens sonic hedgehog signaling molecule (SHH), transcript variant 1, mRNA. 1389 GC-T1004
ICAM1 NM_000201.3 Human Homo sapiens intercellular adhesion molecule 1 (ICAM1), mRNA. 1599 GC-A0111
PDX1 NM_000209.4 Human Homo sapiens pancreatic and duodenal homeobox 1 (PDX1), mRNA. 852 GC-M0942
ITGA6 NM_000210.4 Human Homo sapiens integrin subunit alpha 6 (ITGA6), transcript variant 2, mRNA. 3222 GC-I1372
ITGB3 NM_000212.3 Human Homo sapiens integrin subunit beta 3 (ITGB3), mRNA. 2367 GC-E2219
JAG1 NM_000214.3 Human Homo sapiens jagged canonical Notch ligand 1 (JAG1), mRNA. 3657 GC-M0722
KIT NM_000222.3 Human Homo sapiens KIT proto-oncogene, receptor tyrosine kinase (KIT), transcript variant 1, mRNA. 2931 GC-A0519
PTCH1 NM_000264.5 Human Homo sapiens patched 1 (PTCH1), transcript variant 1b, mRNA. 4344 GC-T0559
RB1 NM_000321.3 Human Homo sapiens RB transcriptional corepressor 1 (RB1), mRNA. 2787 GC-B0065
ATXN7 NM_000333.4 Human Homo sapiens ataxin 7 (ATXN7), transcript variant SCA7a, mRNA. 2679 GC-Y2006
SLC2A2 NM_000340.2 Human Homo sapiens solute carrier family 2 member 2 (SLC2A2), transcript variant 1, mRNA. 1575 GC-C0114
SOX9 NM_000346.4 Human Homo sapiens SRY-box transcription factor 9 (SOX9), mRNA. 1530 GC-M0312
TNNI3 NM_000363.5 Human Homo sapiens troponin I3, cardiac type (TNNI3), mRNA. 633 GC-D0106
TTR NM_000371.4 Human Homo sapiens transthyretin (TTR), mRNA. 444 GC-A0298
AIRE NM_000383.4 Human Homo sapiens autoimmune regulator (AIRE), mRNA. 1638 GC-U1287
HLCS NM_000411.8 Human Homo sapiens holocarboxylase synthetase (HLCS), transcript variant 1, mRNA. 2181 GC-F0424
IFNGR1 NM_000416.3 Human Homo sapiens interferon gamma receptor 1 (IFNGR1), transcript variant 1, mRNA. 1470 GC-A0373
IL2RA NM_000417.3 Human Homo sapiens interleukin 2 receptor subunit alpha (IL2RA), transcript variant 1, mRNA. 819 GC-A0828
ITGA2B NM_000419.5 Human Homo sapiens integrin subunit alpha 2b (ITGA2B), mRNA. 3120 GC-Y4550
L1CAM NM_000425.5 Human Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1, mRNA. 3774 GC-Z2881
PAX3 NM_000438.6 Human Homo sapiens paired box 3 (PAX3), transcript variant PAX3A, mRNA. 648 GC-F0349
PECAM1 NM_000442.5 Human Homo sapiens platelet and endothelial cell adhesion molecule 1 (PECAM1), mRNA. 2217 GC-A3917
HNF4A NM_000457.6 Human Homo sapiens hepatocyte nuclear factor 4 alpha (HNF4A), transcript variant 2, mRNA. 1425 GC-Z2593
HNF1B NM_000458.4 Human Homo sapiens HNF1 homeobox B (HNF1B), transcript variant 1, mRNA. 1674 GC-F0366
BARD1 NM_000465.4 Human Homo sapiens BRCA1 associated RING domain 1 (BARD1), transcript variant 1, mRNA. 2334 GC-Q0613
LDLR NM_000527.5 Human Homo sapiens low density lipoprotein receptor (LDLR), transcript variant 1, mRNA. 2583 GC-A0821
RAG2 NM_000536.4 Human Homo sapiens recombination activating 2 (RAG2), transcript variant 1, mRNA. 1584 GC-H3305
TP53 NM_000546.6 Human Homo sapiens tumor protein p53 (TP53), transcript variant 1, mRNA. 1182 GC-B0105
TPO NM_000547.6 Human Homo sapiens thyroid peroxidase (TPO), transcript variant 1, mRNA. 2802 GC-A4413
IL6R NM_000565.4 Human Homo sapiens interleukin 6 receptor (IL6R), transcript variant 1, mRNA. 1407 GC-A0457
FCGR3B NM_000570.5 Human Homo sapiens Fc gamma receptor IIIb (FCGR3B), transcript variant 2, mRNA. 702 GC-A4239
IL10 NM_000572.3 Human Homo sapiens interleukin 10 (IL10), transcript variant 1, mRNA. 537 GC-A0007
CCR5 NM_000579.4 Human Homo sapiens C-C motif chemokine receptor 5 (CCR5), transcript variant A, mRNA. 1059 GC-Z0659
CD14 NM_000591.4 Human Homo sapiens CD14 molecule (CD14), transcript variant 1, mRNA. 1128 GC-G0084
IGFBP1 NM_000596.4 Human Homo sapiens insulin like growth factor binding protein 1 (IGFBP1), mRNA. 780 GC-O0031
HGF NM_000601.6 Human Homo sapiens hepatocyte growth factor (HGF), transcript variant 1, mRNA. 2187 GC-A0820