All human and mice ORF clones and related Lentivirus, AAV particles and recombinant proteins provided by GeneCopoeia are fully sequenced using Sanger sequencing by capillary electrophoresis and Amino Acid Sequences are guaranteed to be matched with NCBI database.

GeneHero™ CRISPR Products and Services Publications

View selected publications citing GeneCopoeia’s CRISPR products and services from the recent literature

2023

Liu, W., et al. (2023). MCCC2 is a novel mediator between mitochondria and telomere and functions as an oncogene in colorectal cancer. Cell Mol Biol Lett. doi: 10.1186/s11658-023-00487-0 [OMICSLINK™ Human MCCC2 ORF expression clone; GeneHero™ sgRNA clones targeting Human MCCC2]
Dorgham, M.G., et al. (2023). m6A regulates breast cancer proliferation and migration through stage-dependent changes in Epithelial to Mesenchymal Transition gene expression. Front Oncol. doi: 10.3389/fonc.2023.1268977 [GeneHero™ human Cas9 all-in-one expression clone targeting METTL3; GeneHero™ Scrambled sgRNA control for pCRISPR-CG01]
Xu, L., et al. (2023). Generation of Rh D‐negative blood using CRISPR/Cas9. Cell Prolif. doi: 10.1111/cpr.13486 [GeneHero™ Cas9 expressing vector; GeneHero™ AAVS1 Cas9 knock-in clone]
Itson-Zoske, B., et al. (2023). Selective RNAi-silencing of Schwann cell Piezo1 alleviates mechanical hypersensitization following peripheral nerve injury. Res Sq. doi: 10.21203/rs.3.rs-3405016/v1 [GeneHero™ Cas9 expressing stable cell line]
Liesenhoff, C., et al. (2023). Endogenous Galectin-1 Modulates Cell Biological Properties of Immortalized Retinal Pigment Epithelial Cells In Vitro. Int J Mol Sci. doi: 10.3390/ijms241612635 [GeneHero™ human Cas9 all-in-one expression clone targeting LGALS1]
Schuler, B., et al. (2023). Host Lipid Transport Protein ORP1 Is Necessary for Coxiella burnetii Growth and Vacuole Expansion in Macrophages. mSphere doi: 10.1128/msphere.00104-23 [GeneHero™ sgRNA expression clones targeting OSBPL1A]
Naoki, I-T., et al. (2023). The Src-Family Kinases SRC and BLK Contribute to the CLDN6-Adhesion Signaling. Cells doi: 10.3390/cells12131696 [GeneHero™ sgRNA clones targeting mouse Blk; GeneHero™ sgRNA clones targeting mouse Scr]
Talic, E-S., et al. (2023). RNA Methyltransferase METTL16’s Protein Domains Have Differential Functional Effects on Cell Processes. Curr Issues Mol Biol doi: 10.3390/cimb45070346 [GeneHero™ sgRNA control; GeneHero™ METTL16 Cas9-expressing clone]
Schwarz, A.M., et al. (2023). Terpenes from Cannabis sativa Induce Antinociception in Mouse Chronic Neuropathic Pain via Activation of Spinal Cord Adenosine A2A Receptors. bioRxiv doi: 10.1101/2023.03.28.534594 [GeneHero™ Cas9-expressing clone]
Li, C., et al. (2023). SUMO Proteomics Analyses Identify Protein Inhibitor of Activated STAT-Mediated Regulatory Networks Involved in Cell Cycle and Cell Proliferation. J Proteome Res doi: 10.1021/acs.jproteome.2c00557 [GeneHero™ PIAS1、PIAS2、PIAS3、PIAS4 sgRNA clones and negative control]
Lin, P., et al. (2023). TRAF6 regulates the abundance of RIPK1 and inhibits the RIPK1/RIPK3/MLKL necroptosis signaling pathway and affects the progression of colorectal cancer. Cell Death Dis doi: 10.1038/s41419-022-05524-y [GeneHero™ Cas9-expressing clone]
Atobatele, A.G., et al. (2023). Canonical and truncated transglutaminase-2 regulate mucin-1 expression and androgen independency in prostate cancer cell lines. Cell Death Dis doi: 10.1038/s41419-023-05818-9 [GeneHero™ TGM2 sgRNA clones]

2022

Asuthkar, S., et al. (2022). SMYD3 Promotes Cell Cycle Progression by Inducing Cyclin D3 Transcription and Stabilizing the Cyclin D1 Protein in Medulloblastoma. Cancers doi: 10.3390/cancers14071673 [GeneHero™ SMYD3 sgRNA clones]
Zhang, L., et al. (2022). CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cells. Molecular Cancer doi: 10.1186/s12943-022-01524-w [GeneHero™ sgRNA clones targeting CDK6]
Kaneski, C.R., et al. (2022). Generation of an in vitro model for peripheral neuropathy in Fabry disease using CRISPR-Cas9 in the nociceptive dorsal root ganglion cell line 50B11. Molecular Genetics and Metabolism Reports doI; 10.1016/j.ymgmr.2022.100871 [GeneHero™ sgRNA clones targeting GLA]
Domingo-Vidal. M., et al. (2022). Monocarboxylate Transporter 4 in Cancer-Associated Fibroblasts Is a Driver of Aggressiveness in Aerodigestive Tract Cancers. Frontiers in Oncology doi: 10.3389/fonc.2022.906494 [GeneHero™ lentiviral sgRNA clones targeting SLC16A3]
Tontonoz, P. and Kaeberlein, P. (2022). SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B. eLife doi: 10.7554/eLife.67452 [GeneHero™ sgRNA clones targeting mSirt1]

2021

Lee, Y., et al. (2021). Time-of-day specificity ofanticancer drugs may bemediated by circadian regulation ofthecell cycle. Science Advances doi: 10.1126/sciadv.abd2645 [GeneHero™ sgRNA clones]
Li, X., et a. (2021). Enhancing Gene Editing Efficiency for Cells by CRISPR/Cas9 System-Loaded Multilayered Nanoparticles Assembled via Microfluidics. Chinese Journal of Chemical Engineering doi: 10.1016/j.cjche.2021.02.009 [GeneHero™ Cas9-expressing clone]
Kwik, M., et al. (2021). Selective Activation of CNS and ReferencePPARGC1APromoters Is Associated with Distinct Gene Programs Relevantfor Neurodegenerative Diseases. International Journal of Molecular Sciences doi: 10.3390/ijms22073296 [GeneHero™ sgRNA clones]
Huo, X., et al. (2021). MicroRNA-4325 Suppresses Cell Progression in Hepatocellular Carcinoma via GATA-Binding Protein 6. BioMed Research International doi: 10.1155/2021/6616982 [GeneHero™ sgRNA clones targeting GATA6]
Hara, T., et al. (2021). Glyoxalase I disruption and external carbonyl stress impair mitochondrial function in human induced pluripotent stem cells and derived neurons. Translational Psychiatry doi: 10.1038/s41398-021-01392-w [GeneHero™ donor clone]
Ray, U., et al. (2021). Group III phospholipase A2 downregulation attenuated survival and metastasis in ovarian cancer and promotes chemo-sensitization. Journal of Experimental & Clinical Cancer Research doi: 10.1186/s13046-021-01985-9 [GeneHero™ sgRNA clones targeting PLA23G]
Woo, H-H. and Chambers, S.K. (2021). Regulation of closely juxtaposed protooncogene c-fms and HMGXB3 gene expression by mRNA 3’end polymorphism in breast cancer cells. RNA doi: 10.1261/rna.078749.121 [GeneHero™ donor clone]
Chafe, S.C., et a. (2021). Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors. Science Advances doi: 10.1126/sciadv.abj0364 [GeneHero™ sgRNA clones]
Xia, L., et al. (2021). Multiplatform discovery and regulatory function analysis of structural variations in non-small cell lung carcinoma. Cell Reports doi: 10.1016/j.celrep.2021.109660 [GeneHero™ sgRNA and HDR donor clones]
Dzakah, E.E., et al. (2021). Chlamydia trachomatis stimulation enhances HIV-1 susceptibility via the modulation of a member of the macrophage inflammatory proteins. Journal of Investigative Dermatology doi: 10.1016/j.jid.2021.09.020 [GeneHero™ lentiviral sgRNA clones]
Szaflarski, W. , et al. (2021). Early rRNA processing is a stress-dependent regulatory event whose inhibition maintains nucleolar integrity. Nucleic Acids Research doi: 10.1093/nar/gkab1231 [GeneHero™ sgRNA and HDR donor clones]

2020

Frendewey, D., et al. (2020). METHODS AND COMPOSITIONS FOR TARGETED GENETIC MODIFICATION USING PAIRED GUIDE RNAS. United States Patent Application 20200002730 [GeneHero™ sgRNA clones targeting Lrp5]
Zhang, L., et al. (2020). The PI3K subunits, P110α and P110β are potential targets for overcoming P-gp and BCRP-mediated MDR in cancer. Molecular Cancer doi: 10.1186/s12943-019-1112-1 [GeneHero™ sgRNA clones targeting PIK3CA, PIK3CB]
Chen, P., et al. (2020). High RhCG expression predicts poor survival and promotes migration and proliferation of gastric cancer via keeping intracellular alkaline. Experimental Cell Research doi: 10.1016/j.yexcr.2019.111740 [GeneHero™ sgRNA clone]
López, S.M., et al. (2020). Challenges associated with homologous directed repair using CRISPR-Cas9 and TALEN to edit the DMD genetic mutation in canine Duchenne muscular dystrophy. PLOS ONE doi: 10.1371/journal.pone.0228072 [GeneHero™ sgRNA clones and donor clone targeting canine DMD]
Joshi, A., et al. (2020). The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis. BMC Biology doi: 10.1186/s12915-020-0740-7 [GeneHero™ sgRNA clones targeting UMUC3]
Li, C., et al. (2020). Quantitative SUMO proteomics identifies PIAS1 substrates involved in cell migration and motility, Nature Communications doi: 10.1038/s41467-020-14581-w [GeneHero™ sgRNA clones targeting PIAS]
Stinger, R.N., et al. (2020). A rare CACNA1H variant associated with amyotrophic lateral sclerosis causes complete loss of Cav3.2 T-type channel activity. Molecular Brain doi: 10.1186/s13041-020-00577-6 [GeneHero™ sgRNA clones and donor clone]
Renema, P., et al. (2020). cAMP signaling primes lung endothelial cells to activate caspase-1 during Pseudomonas aeruginosa infection. American Journal of Physiology-Lung Cellular and Molecular Physiology doi: 10.1152/ajplung.00185.2019 [GeneHero™ sgRNA clones targeting Rat Casp1]
Nakazawa, T., et al. (2020).E ect of CRISPR/Cas9-Mediated PD-1-Disrupted Primary Human Third-Generation CAR-T Cells Targeting EGFRvIII on In Vitro Human Glioblastoma Cell Growth. Cells doi: 10.3390/cells9040998 [GeneHero™ sgRNA clones]
Lin, C-L., et al. (2020). ERα-related chromothripsis enhances concordant gene transcription on chromosome 17q11.1-q24.1 in luminal breast cancer. BMC Medical Genomics doi: 10.1186/s12920-020-0729-7 [GeneHero™ sgRNA clones]
Meinhardt, G., et al. (2020). Pivotal role of the transcriptional co-activator YAP in trophoblast stemness of the developing human placenta . Proceedings of the National Academy of Scienes of the United States of America doi: 10.1073/pnas.2002630117 [GeneHero™ sgRNA clones targeting YAP]
Matsui, M., et al. (2020). USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA–RNA helicase DHX9. Oncogenesis doi: 10.1038/s41389-020-00244-4 [GeneHero™ donor clone]
Chen, Y., et al. (2020). Knockdown of LINC00662 represses AK4 and attenuates radioresistance of oral squamous cell carcinoma. Cancer Cell International doi: 10.1186/s12935-020-01286-9 [GeneHero™ LINC00662 lentiviral sgRNA clone set]
Nelson, J., et al. (2020). Impact of mRNA chemistry and manufacturing process on innate immune activation. Science Advances doi: 10.1126/sciadv.aaz6893 [GeneHero™ sgRNA clones targeting MAVS]
Schweitzer, K.S., et al. (2020). IGSF3 mutation identified in patient with severe COPD alters cell function and motility. JCI insight doi: 10.1172/jci.insight.138101 [GeneHero™ sgRNA clones targeting Beas2B]
Badaoui, M., et al. (2020). Vav3 Mediates Pseudomonas aeruginosa Adhesion to the Cystic Fibrosis Airway Epithelium. Cell Reports doi: 10.1016/j.celrep.2020.107842 [GeneHero™ leniviral particles expressing sgRNA clones targeting Vav3]
Renema, P., et al. (2020). cAMP signaling primes lung endothelial cells to activate caspase-1 during Pseudomonas aeruginosa infection. American Journal of Physiology – Lung Cellular and Molecular Physiology doi: 10.1152/ajplung.00185.2019 [GeneHero™ sgRNA clones targeting caspase-1]
Feng, Y.C., et al. (2020). c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis. Nature Communications doi: 10.1038/s41467-020-18735-8 [GeneHero™ CRISPRi sgRNA clones targeting MILIP]
Wang, L., et al. (2020). Inhibition of the ATM/Chk2 axis promotes cGAS/STING signaling in ARID1A-deficient tumors. The ournal of Clinical Investigation doi: 10.1172/JCI130445 [GeneHero™ sgRNA clones targeting Arid1a]
Wrobel, N., et al. (2020). mTORC2 Assembly Is Regulated by USP9X-Mediated Deubiquitination of RICTOR. Cell Reports doi: 10.1016/j.celrep.2020.108564 [Secrete-Pair™ Dual Luminescence Assay Kit]

2019

Gürtler, S., et al. (2019). Tafazzin-dependent cardiolipin composition in C6 glioma cells correlates with changes in mitochondrial and cellular functions, and cellular proliferation. Biochimica et Biophysica Acta (BBA) – Molecular and Cell Biology of Lipids doi: 10.1016/j.bbalip.2019.01.006 [GeneHero™ sgRNA clones targeting Taz1]
Wang, Z., et al. (2019). DNA Polymerase theta (POLQ) is important for repair of DNA double-strand breaks caused by fork collapse. The Journal of Biological Chemistry doi: 10.1074/jbc.RA118.005188 [GeneHero™ sgRNA clones targeting POLQ]
Adams, J., et al. (2019). Autophagy–lysosome pathway alterations and alpha-synuclein up-regulation in the subtype of neuronal ceroid lipofuscinosis, CLN5 disease. Scientific Reports doi: 10.1038/s41598-018-36379-z [GeneHero™ sgRNA clones targeting SNCA]
Geng, Y., et al. (2019). PD-L1 on invasive fibroblasts drives fibrosis in a humanized model of idiopathic pulmonary fibrosis. JCI Insight [GeneHero™ sgRNA clone targeting CD274]
Zheng, Y-L., et al. (2019). LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway. Theranostics doi: 10.7150/thno.28992 [GeneHero™ sgRNA clones targeting LINC01554]
Pushpavathi, G., et al. (2019). CRISPR/Cas9 Editing of Glia Maturation Factor Regulates Mitochondrial Dynamics by Attenuation of the NRF2/HO-1 Dependent Ferritin Activation in Glial Cells. Journal of Neuroimmune Pharmacology doi: 10.1007/s11481-019-09833-6 [GeneHero™ lentiviral sgRNA clones]
Zang, J., et al. (2019). Glucose drives growth factor-independent esophageal cancer proliferation viaphosphohistidine-FAK signaling. Cellular and Molecular Gastroenterology and Hepatology doi:10.1016/j.jcmgh.2019.02.009 [GeneHero™ sgRNA clones targeting PTK2]
Zhang, D., et al. (2019). Chromogranin A regulates neuroblastoma proliferation and phenotype. Biology Open doi: 10.1242/bio.036566 [GeneHero™ sgRNA clones targeting CHGA]
Ji, J., et al. (2019). FOXO1 Overexpression Attenuates Tubulointerstitial Fibrosis and Apoptosis in Diabetic Kidneys by Ameliorating Oxidative Injury via TXNIP-TRX. Oxidative Medicine and Cellular Longevity doi: 10.1155/2019/3286928 [GeneHero™ sgRNA clones targeting FOXO1]
Pradhan, A.K., et al. (2019). MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF. Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.1819869116 [GeneHero™ sgRNA clones targeting MDA-7/IL-24]
Ghoshal, A., et al. (2019). Extracellular vesicle-dependent effect of RNA-binding protein IGF2BP1 on melanoma metastasis. Oncogene doi: 10.1038/s41388-019-0797-3 [GeneHero™ sgRNA clones targeting IGF2BP1]
Pan, C., et al. (2019). Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance. Journal of Clinical INvestigation doi: 10.1172/JCI124550DS1 [GeneHero™ lentiviral sgRNA clones targeting IGF2BP1]
Ramakrishnan, A. (2019). DISC1 is needed for the organization of cellular components at the immunological synapse. Ph.D. Thesis, University of Texas [GeneHero™ lentiviral sgRNA clones targeting DISC1]
Wall, C.E., et al. (2019). PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin. Cell Reports doi: 10.1016/j.celrep.2019.10.130 [GeneHero™ sgRNA clones targeting PPEF2]
Narimani, M., et al. (2019). Knockout Of BIRC5 Gene By CRISPR/Cas9 Induces Apoptosis And Inhibits Cell Proliferation In Leukemic Cell Lines, HL60 And KG1/. Blood and Lymphatic Cancer: Targets and Therapy doi: 10.2147/BLCTT.S230383 [GeneHero™ sgRNA clones]
Turturro, S.B., et al. (2019). Somatic loss of PIK3R1 may sensitize breast cancer to inhibitors of the MAPK pathway. Breast Cancer Research and Treatment doi: 10.1007/s10549-019-05320-x [GeneHero™ sgRNA clones]
Sussman, W., et al. (2019). BMAL1 controls glucose uptake through paired-homeodomain transcriptionfactor 4 in differentiated Caco-2 cells. American Journal of Physiology-Cell physiology doi: 10.1152/ajpcell.00058.2019 [GeneHero™ sgRNA clones targeting PAX4]
Kulbay, M., et al. (2019). DNA fragmentation factor 40 expression in T cells confers sensibility to tributyltin-induced apoptosis. Toxicology doi: 10.1016/j.tox.2019.152255 [GeneHero™ sgRNA clones]
Barrow, M.A., et a. (2019). A functional role for the cancer disparity-linked genes, CRYβB2 and CRYβB2P1, in the promotion of breast cancer. Breast Cancer Research doi: 10.1186/s13058-019-1191-3 [GeneHero™ sgRNA clones]
Kuo, T., et al. (2019). Identification of C2CD4A as a human diabetes susceptibility gene with a role in β cell insulin secretion. Proceedingsof the National Academy of Sciences of the United States of America doi: 10.1073/pnas.1904311116 [GeneHero™ sgRNA clones targeting C2CD4A]
Fujimoto, B.A., et al. (2019). The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells. American Journal of Physiology-Enocrinology and Metabolism doi: 0.1152/ajpendo.00109.2019 [GeneHero™ sgRNA clones]
Yu, W., et al. (2019). Higher expression of SATB2 in hepatocellular carcinoma of African Americans determines more aggressive phenotypes than those of Caucasian Americans. Journal of Cellular and Molecular Medicine doi: 10.1111/jcmm.14652 [GeneHero™ lentiviral CRISPR clones targeting SATB2]
Gohari, I.M., et al. (2019). Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells. Toxins doi: 10.3390/toxins11100582 [GeneHero™ CRISPR clones targeting Claudin-1]

2018

Kanda, Y., et al. (2018). TRPA1-dependent reversible opening of tight junction by natural compounds with an α,β-unsaturated moiety and capsaicin. Scientific Reports doi: 10.1038/s41598-018-20526-7 [Genome-CRISP™ sgRNA clones targeting TRPA1]
Chen, X., et al. (2018). A spliced form of CD44 expresses the unique glycan that is recognized by the prostate cancer specific antibody F77. Ocotarget doi: 10.18632/oncotarget.23341 [Genome-CRISP™ CRISPR-Cas9 constructs]
Maier, M., et al. (2018). The Role of Trio, a Rho Guanine Nucleotide Exchange Factor, in Glomerular Podocytes. International Journal of Molecular Sciences doi: 10.3390/ijms19020479 [Genome-CRISP™ lentiviral clone expressing sgRNA targeting Trio]
Norouzi-Barough, L., et al. (2018). Bioinformatics design of CRISPR guide RNA for genomic knockout of ABCB1 gene. Biotech Health Sci . 2018 Feb; 4(3):e58783 [Genome-CRISP™ clones expressing sgRNA targeting ABCB1]
Raikwar, S.P., et al. (2018). Targeted Gene Editing of Glia Maturation Factor in Microglia: a Novel Alzheimer’s Disease Therapeutic Target. Molecular Neurobiology doi: 10.1007/s12035-018-1068-y [Genome-CRISP™ lentiviral clones expressing sgRNA targeting GMF]
Shen, J., et al. (2018). ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade. Nature Medicine doi: 10.1038/s41591-018-0012-z [Genome-CRISP™ lentiviral clones expressing sgRNA targeting ARID1A]
Huang, H., et al. (2018). EP300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis. Molecular Cell doi: 10.1016/j.molcel.2018.04.011 [Genome-CRISP™ clones expressing sgRNA targeting EP300]
Dakhama, A. and Chu, H-W. (2018). The Use of CRISPR-Cas9 Technology to Reveal Important Aspects of Human Airway Biology. Type 2 Immunity doi: 10.1007/978-1-4939-7896-0_27 [Lentiviral CRISPR clones]
Li, Y., et al. (2018). Histone H1 acetylation at lysine 85 regulates chromatin condensation and genome stability upon DNA damage, Nucleic Acids Research doi: 10.1093/nar/gky568 [Lentiviral CRISPR clones]
Sharlati, L., et al. (2018). Disruption of SOX6 gene using CRISPR/Cas9 technology for gamma‐globin reactivation: An approach towards gene therapy of β‐thalassemia. Journal of Cellular Biochemistry doi: 10.1002/jcb.27253 [CRISPR clones]
Suganuma, T., et al. (2018). MPTAC Determines APP Fragmentation via Sensing Sulfur Amino Acid Catabolism. Cell Reports doi: 10.1016/j.celrep.2018.07.013 [Genome-CRISP™ clone expressing sgRNA targeting MOCS2]
Hulea, L., et al. (2018). Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides. Cell Metabolism doi: 10.1016/j.cmet.2018.09.001 [GeneHero™ clones expressing sgRNAs targeting h4E-BP1, h4E-BP2, m4E-BP1, m4E-BP2]
Seturuman, A., et al. (2018). BHLHE40 confers a pro-survival and pro-metastatic phenotype to breast cancer cells by modulating HBEGF secretion. Breast Cancer Research doi: 10.1186/s13058-018-1046-3 [GeneHero™ clone expressing sgRNA targeting BHLHE40]
Raas, Q., et al. (2018). A microglial cell model for acyl-CoA oxidase 1 deficiency. Biochimica et Biophysica Acta (BBA) – Molecular and Cell Biology of Lipids doi: 10.1016/j.bbalip.2018.10.005 [GeneHero™ clone expressing sgRNA]
Wei, N., et al. (2018). Targeting colon cancer with the novel STAT3 inhibitor bruceantinol. Oncogene doi: 10.1038/s41388-018-0547-y [GeneHero™ clone expressing sgRNA targeting STAT3]
Gulyaeva, O., et al. (2018). Sox9-Meis1 Inactivation Is Required for Adipogenesis, Advancing Pref-1+ to PDGFRα+ Cells. Cell Reports doi:10.1016/j.celrep.2018.09.086 [GeneHero™ clone expressing sgRNA targeting Meis1]
Chua, M.D., et al. (2018). Klebsiella pneumoniae disassembles host microtubules in lung epithelial cells. Cellular Microbiology doi: 10.1111/cmi.12977 [GeneHero™ clones expressing sgRNA targeting KANAL1, KATNB1]
Raas, Q., et al. (2018). A microglial cell model for acyl-CoA oxidase 1 deficiency. BBA – Molecular and Cell Biology of Lipids doi: 10.1016/j.bbalip.2018.10.005 [GeneHero™ clone expressing sgRNA targeting Acox1]

Teng, Y., et al. (2017). MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression. Nature Communications doi: 10.1038/ncomms14448 [Lentiviral particles expressing sgRNA targeting MVP]
Shen, J.P., et al. (2017). Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions. Nature Methods doi 10.1038/nmeth.4225 [HeLa, HEK293T and A549 Cas9-expressing stable cell lines]
Blanco, G., et al. (2017). IGFN1_v1 is required for myoblast fusion and differentiation. PLoS ONE, In press. [sgRNA and donor clones targeting Igfn1 exon 13]
Ji, Q., et al. (2017). Genetically engineered cell lines for α1-antitrypsin expression. Biotechnology Letters doi: 10.1007/s10529-017-2391-5 [Genome-CRISP™ human AAVS1 Safe Harbor Knock-in kit and AAT knock-in ORF donor clone].
Jin, K., et al. (2017). Crosstalk between stromal components and tumor cells of TNBC via secreted factors enhances tumor growth and metastasis. Oncotarget doi:10.18632/oncotarget.19417 [Genome-CRISP™ sgRNA clones targeting CXCR2]
Leonova, K., et al. (2017). Transcription of Repeats Activates INterfern (TRAIN) in response to chromatin destabilization induced with anti-cancer small molecule, bioRxiv doi: 10.1101/142471 [Genome-CRISP™ sgRNA clones targeting ZBP1]
Bartolomeo, R., et al. (2017). mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. The Journal of Clinical Investigation doi: 10.1172/JCI94130 [Genome-CRISP™ sgRNA clone targeting Gusb]
Morita, M., et al. (2017). mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1. Molecular Cell doi: 10.1016/j.molcel.2017.08.013 [Genome-CRISP™ sgRNA clones targeting 4E-BP1 and 4E-BP2]
Subramaniam, M., et al. (2017). TIEG and estrogen modulate SOST expression in the murine skeleton. Journal of Cellular Physiology doi: 10.1002/jcp.26211 [Genome-CRISP™ sgRNA clone targeting TIEG]
Murao, N., et al. (2017). Essential roles of aspartate aminotransferase 1 and vesicular glutamate transporters in β -cell glutamate signaling for incretin-induced insulin secretion. PLoS ONE doi: 10.137 1/journal.po ne.01872 [Cas9 D10 nickase expression clone and sgRNA expression clones]
Borque, C., et al. (2017). H2S protects lipopolysaccharide-induced inflammation by blocking NFκB transactivation in endothelial cells. Toxicology and Applied Pharmacology doi: 10.1016/j.taap.2017.11.004 [Genome-CRISP™ CRISPR-Cas9 clone for CSE gene knockout]
Fan, Q., et al. (2017). The novel ZIP4 regulation and its role in ovarian cancer. Oncotarget doi: 10.18632/oncotarget.21435 [ZIP4 and PPARr lentiviral CRISPR vectors]
Sun, X., et al. (2017). Purple Potato Extract Promotes Intestinal Epithelial Differentiation and Barrier Function by Activating AMP-Activated Protein Kinase. Molecular Nutrition and Food Research doi: 10.1002/mnfr.201700536 [AMPK CRISPR vectors]
Huang, F., et al. (2017). δ-Catenin promotes tumorigenesis and metastasis of lung adenocarcinoma. Oncology Reports doi: 10.3892/or.2017.6140 [Genome-CRISP™ CRISPR-Cas9 clone for Ctnnd2 gene knockout]
Shuang, T., et al. (2017). The interaction of IGF-1/IGF-1R and hydrogen sulfide on the proliferation of mouse primary vascular smooth muscle cells. Biochemical Pharmacology doi: 10.1016/j.bcp.2017.12.009 [Genome-CRISP™ CRISPR-Cas9 clone for IGF-1R gene knockout]
Jin, L., et al. (2017). The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer. Molecular Cell doi: 10.1016/j.molcel.2017.11.025 [Genome-CRISP™ CRISPR-Cas9 clones for LKB1 and CamKK2 gene knockout]

Qi, C. et al. (2016) HEK293T Cells Are Heterozygous for CCR5 Delta 32 Mutation. PLOS ONE, April 4, 2016 http://dx.doi.org/10.1371/journal.pone.0152975. [T7E1 nuclease].
Hsu, PY. et al. (2016) Spatiotemporal control of estrogen-responsive transcription in ERα-positive breast cancer cells. Oncogene, 35, 2379–2389; doi:10.1038/onc.2015.298; published online 24 August 2015. [DEREs, sgRNA contructs and validation].
Blackburn, JB. Et al. (2016) COG Complex complexities: Detailed characterization of a complete set of HEK293T cells lacking individual COG subunits. Frontiers in Cell and Developmental Biology, 2016; 4: 23. [Cog5, Cog2, Cog7 sgRNA].
Hu, B., et al. (2016). A Novel Missense Mutation of CMT2P Alters Transcription Machinery. Annals of Neurobiology doi: 10.1002/ana.24776 [LRSAM1 CRISPR sgRNA clone]
Bahal, R., et al. (2016). In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery. Nature Communications doi: 10.1038/ncomms13304 [Cas9 and sgRNA clones targeting mouse b-globin]

Zhang, J. et al. (2015) Focal adhesion kinase-promoted tumor glucose metabolism is associated with a shift of mitochondrial respiration to glycolysis. Oncogene, 35, 1926-1942 (14 April 2016) | doi:10.1038/onc.2015.256-. [CRISPR-Cas9 genome editing system for FAK]
Wu, J. et al. (2015) Decreased RECQL5 correlated with disease progression of osteosarcoma. Biochemical and Biophysical Research Communications, Volume 467, Issue 4, 27 November 2015, Pages 617–622. [AAVS1 safe harbor gene knock-in kit]
Foss, O. et al. (2015) Role of FOXA genes in maintaining transformed phenotype in human bronchial epithelial cells. NTNU Open, 2015. [FOXA1 gene, sgRNA, donor, AAVS1 safe harbor gene knock-in kit].
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