See select publications from scientists who took the GeneCopoeia Expressway to Discovery

microRNA collections:

• Kim, H W et al. (2009) Ischemic Preconditioning Augments Survival of Stem Cells via miR-210 Expression by Targeting Caspase-8-associated Protein 2*. The Journal of Biological Chemistry 284(48):33161–33168. [pEZX-miR-210 and luciferase reporter construct containing the 3-UTR of Casp8ap2]

cDNA clone collections:

• Small GTPase Determinants for the Golgi Processing and Plasmalemmal Expression of Human Ether-a-go-go Related (hERG) K+ Channels, Brian P. Delisle, Heather A. S. Underkofler, Brooke M. Moungey, Jessica K. Slind, Jennifer A. Kilby, Jabe M. Best, Jason D. Foell, Ravi C. Balijepalli, Timothy J. Kamp, and Craig T. January, J. Biol. Chemistry, Vol. 284, Issue 5, 2844-2853, January 2009, (Rab Transcripts)
• Specific Biarsenical Labeling of Cell Surface Proteins Allows Fluorescent- and Biotin-tagging of Amyloid Precursor Protein and Prion Proteins, Yuzuru Taguchi, Zhen-Dan Shi, Brian Ruddy, David W. Dorward, Lois Greene, and Gerald S. Baron,MBC Online, Vol. 20, Issue 1, 233-244, January 1, 2009, [APP695, (EX-F0776-M02)]
• Immunohistochemical detection, regulation and antiproliferative function of G-protein-coupled receptor kinase 2 in thyroid carcinomas, Thierry Métayé, Pierre Levillain, Jean-Louis Kraimps and Rémy Perdrisot, Journal of Endocrinology (2008) 198, 101-110, (GRK2)
• Dynamic Coupling of the Putative Coiled-coil Domain of ORAI1 with STIM1 Mediates ORAI1 Channel Activation, Martin Muik, Irene Frischauf, Isabella Derler, Marc Fahrner, Judith Bergsmann, Petra Eder, Rainer Schindl, Clemens Hesch, Bernhard Polzinger, Reinhard Fritsch, Heike Kahr, Josef Madl, Hermann Gruber, Klaus Groschner, and Christoph Romanin, The Journal of Biological Chemistry, VOL. 283, NO. 12, pp. 8014–8022, March 21, 2008, [C-terminally EYFP-tagged STIM1, (EX-S0521-M02, M16)]
• PKR Regulates B56α-mediated BCL2 Phosphatase Activity in Acute Lymphoblastic Leukemia-derived REH Cells, Vivian R. Ruvolo, Svitlana M. Kurinna, Kul B. Karanjeet, Todd F. Schuster, Alberto M. Martelli, James A. McCubrey, and Peter P. Ruvolo, J. Biol. Chem., Vol. 283, Issue 51, 35474-35485, December 19, 2008, (N-terminal HA-tagged PPP2R5A)
• A Human Bone Morphogenetic Protein Antagonist Is Down-Regulated in Renal Cancer, Kimberly Rose Blish, Wei Wang, Mark C. Willingham, Wei Du, Charles E. Birse, Surekha R. Krishnan, Julie C. Brown, Gregory A. Hawkins, A. Julian Garvin, Ralph B. D'Agostino, Jr., Frank M. Torti, and Suzy V. Torti, MBC Online, Vol. 19, Issue 2, 457-464, February 2008, [BMP-7 (pReceiver-M2-BMP7), dickkopf-1 (pReceiver- M2-DKK1), noggin (pReceiver-M02-noggin), and Wnt-3a (pReceiver-M02-Wnt3a)]
• Down-Regulation of Hedgehog-Interacting Protein through Genetic and Epigenetic Alterations in Human Hepatocellular Carcinoma, Motohisa Tada, Fumihiko Kanai, Yasuo Tanaka, Keisuke Tateishi, Miki Ohta, Yoshinari Asaoka, Motoko Seto, Ryosuke Muroyama, Kenichi Fukai, Fumio Imazeki, Takao Kawabe, Osamu Yokosuka and Masao Omata, Clinical Cancer Research 14, 3768-3776, June 15, 2008,  (HHIP)
• Cathepsin G Enhances Mammary Tumor–Induced Osteolysis by Generating Soluble Receptor Activator of Nuclear Factor-κB Ligand, Thomas J. Wilson, Kalyan C. Nannuru, Mitsuru Futakuchi, Anguraj Sadanandam and Rakesh K. Singh, Cancer Research 68, 5803-5811, July 15, 2008, [(RANKL (NM_003701) His-tagged in pReceiver-B01)]
• Vimentin Filaments Support Extension of Tubulin-Based Microtentacles in Detached Breast Tumor Cells, Rebecca A. Whipple, Eric M. Balzer, Edward H. Cho, Michael A. Matrone, Jennifer R. Yoon and Stuart S. Martin, Cancer Research 68, 5678-5688, July 15, 2008, (Vimentin eGFP tagged in pReceiver-M29)
• STIM1–Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy, Navarro-Borelly, Laura; Somasundaram, Agila; Yamashita, Megumi; Ren, Dongjun; Miller, Richard J.; Prakriya, Murali,  The Journal of Physiology, Volume 586, issue 22, p. 5383-5401, November 15, 2008, (N-terminally tagged CFP–Orai1)
• C-Reactive Protein Enhances Tissue Factor Expression by Vascular Smooth Muscle Cells, Mechanisms and In Vivo Significance, Jianbo Wu; Meredith J. Stevenson; Jordan M. Brown; Elizabeth A. Grunz; Tammy L. Strawn; William P. Fay, Arteriosclerosis, Thrombosis, and Vascular Biology. 2008;28:698, (CRP in pReceiver-M03)
• Jouberin localizes to collecting ducts and interacts with nephrocystin-1, Lorraine Eley, Christos Gabrielides, Matthew Adams, Colin A Johnson, Friedhelm Hildebrandt, John A Sayer, Kidney International (2008) 74, 1139–1149, (Nephrocystin and p130Cas both tagged with 3XFLAG)
• Selective activation of NFAT by promyelocytic leukemia protein, Y-H Lo, C-C Wu, H-M Shih, M-Z Lai, Oncogene (2008) 27, 3821–3830, (PML-I)
•  Targeting of the F-actin-binding protein drebrin by the microtubule plus-tip protein EB3 is required for neuritogenesis , Sara Geraldo, Umme K. Khanzada, Maddy Parsons, John K. Chilton, Phillip R. Gordon-Weeks, Nature Cell Biology 10, 1181 - 1189 (2008), [DBN1 (Accn: D17530)]
•  Ubiquitin binding and conjugation regulate the recruitment of Rabex-5 to early endosomes, Rafael Mattera and Juan S Bonifacino, The EMBO Journal (2008) 27, 2484–2494, (HA tagged Rab5a, Rab5b & Rab5c in pReceiver-M06)
•  SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout, Veronique Vitart, Igor Rudan, Caroline Hayward, Nicola K Gray, James Floyd, Colin NA Palmer, Sara A Knott, Ivana Kolcic, Ozren Polasek, Juergen Graessler, James F Wilson, Anthony Marinaki, Philip L Riches, Xinhua Shu, Branka Janicijevic, Nina Smolej-Narancic, Barbara Gorgoni, Joanne Morgan, Susan Campbell, Zrinka Biloglav, Lovorka Barac-Lauc, Marijana Pericic, Irena Martinovic Klaric, Lina Zgaga, Tatjana Skaric-Juric, Sarah H Wild, William A Richardson, Peter Hohenstein, Charley H Kimber, Albert Tenesa, Louise A Donnelly, Lynette D Fairbanks, Martin Aringer, Paul M McKeigue, Stuart H Ralston, Andrew D Morris, Pavao Rudan, Nicholas D Hastie, Harry Campbell & Alan F Wright, Nature Genetics 40, 437 - 442 (2008), [Gateway-compatible entry clones T3097 (SLC2A9_S or GLUT9DN) and T4563 (URAT1 or SLC22A12)] 
• Recombinant, refolded tetrameric p53 and gonadotropinreleasing hormone-p53 slow proliferation and induce apoptosis in p53-deficient cancer cells, Michelle LaFevre-Bernt,1 Shili Wu,1 and Xinli Lin1,2, Molecular Cancer Therapeutics 7, 1420-1429, June 1, 2008, (Wild-type p53)
•  Regulation of Glycogen Synthase Kinase 3β Functions by Modification of the Small Ubiquitin-Like Modifier, Eun Jeoung Lee, Sung Hee Hyun, Jaesun Chun, Sung Hwa Shin, Kwang Hum Yeon, Min Kyoung Kwak, Tae Yoon Park and Sang Sun Kang, The Open Biochemistry Journal, 2008, 2, 67-76, (GSK 3β Ha- or GST-tagged)
• Notch Activation Is Associated with Tetraploidy and Enhanced Chromosomal Instability in Meningiomas1, Gilson S. Baia, Stefano Stifani, Edna T. Kimura,Michael W. McDermott, Russell O. Pieper and Anita Lal, Neoplasia (2008) 10, 604–612, (HES1)
• S-Glutathionylation Impairs STAT3 Activation and Signaling, Yi Xie1, Sutapa Kole2, Patricia Precht3, Michael J. Pazin3, and Michel Bernier1, Endocrinology,doi:10.1210/en.2008-1241, [(GRX)-1 in pReceiver-M15]
• The Proline-rich Akt Substrate of 40 kDa (PRAS40) Is a Physiological Substrate of Mammalian Target of Rapamycin Complex 1, Noriko Oshiro, Rinako Takahashi, Ken-ichi Yoshino, Keiko Tanimura, Akio Nakashima, Satoshi Eguchi, Takafumi Miyamoto, Kenta Hara, Kenji Takehana, Joseph Avruch, Ushio Kikkawa, and Kazuyoshi Yonezawa, J. Biol. Chem., Vol. 282, Issue 28, 20329-20339, July 13, 2007,  (pReceiver-MO1-His6-PRAS40)
• Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot–Marie–Tooth disease-linked mutations in NFL and HSPB1, Jinbin Zhai, Hong Lin, Jean-Pierre Julien and William W. Schlaepfer, Human Molecular Genetics 2007, 16(24):3103-3116, [(pReceiver-M02/hNFL) or (pReceiver-M03/hNFL-GFP)]
• A new PET tracer specific for vascular endothelial growth factor receptor 2, Hui Wang &Weibo Cai & Kai Chen & Zi-Bo Li & Amir Kashefi & Lina He & Xiaoyuan Chen, Eur J Nucl Med Mol Imaging (2007) 34:2001–2010, (VEGFR-1)
• Androgen receptor decoy molecules block the growth of prostate cancer, Steven N. Quayle, Nasrin R. Mawji, Jun Wang, and Marianne D. Sadar, PNAS January 23, 2007 vol. 104 no. 4 1331-1336, (GRα)
• Protein Microarray Technology, David A. Hall, Jason Ptacek, and Michael Snyder, Mech Ageing Dev. 2007 January; 128(1): 161–167
• A Bioinformatics Approach to Identifying Tail-Anchored Proteins in the Human Genome, Ted Kalbfleisch, Alex Cambon and Binks W. Wattenberg, Traffic 2007; 8: 1687–1694, (RARRES3 and HRASLS3 FLAG-tagged in pReceiver-MII)
• HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system, Jason L DeHart, Erik S Zimmerman, Orly Ardon, Carlos MR Monteiro-Filho, Enrique R Argañaraz and Vicente Planelles, Virology Journal 2007, 4:57, (Flag-DCAF1)
• Enhancement of cell proliferation in various mammalian cell lines by gene insertion of a cyclin-dependent kinase homolog, Pratik Jaluria, Michael Betenbaugh, Konstantinos Konstantopoulos and Joseph Shiloach, BMC Biotechnology 2007, 7:71 (Plasmid containing the full-length cDNA)
• Single Amino Acid Changes in the Nipah and Hendra Virus Attachment Glycoproteins Distinguish EphrinB2 from EphrinB3 Usage, Oscar A. Negrete, David Chu, Hector C. Aguilar, and Benhur Lee, Journal of Virology, October 2007, p. 10804-10814, Vol. 81, No. 19, (Human ephrinB2 and ephrinB3 plasmids)
• NF-kB mediates the transcription of mouse calsarcin-1 gene, but not calsarcin-2, in C2C12 cells, Heng Wang, Shulin Yang, E Yang, Zhengmao Zhu, Yulian Mu, Shutang Feng and Kui Li, BMC Molecular Biology 2007, 8:19,  (pReceiver-MEF2C, encoding p50 and MEF2C)
• TGFβ Protein Processing and Activity through TCR Triggering of Primary CD8+ T Regulatory Cells, Antoine   Ménoret, Lara M. Myers, Seung-Joo Lee, Robert S. Mittler, Robert J. Rossi and Anthony T. Vella, The Journal of Immunology, 2006, 177: 6091-6097, (Recombinant mature and latent TGFβ)
• Interaction of Methotrexate with Organic-Anion Transporting Polypeptide 1A2 and Its Genetic Variants, Ilaria Badagnani, Richard A. Castro, Travis R. Taylor, Claire M. Brett, Conrad C. Huang, Douglas Stryke, Michiko Kawamoto, Susan J. Johns, Thomas E. Ferrin, Elaine J. Carlson, Esteban G. Burchard, and Kathleen M. Giacomini, The Journal of Pharmacology and Experimental Therapeutics, 318:521-529, 2006, (SLCO1A2)
Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3, W. Brian Saunders, Brenda L. Bohnsack, Jennifer B. Faske, Nicholas J. Anthis, Kayla J. Bayless, Karen K. Hirschi,and George E. Davis, JCB, Volume 175, Number 1, 179-191, October 2006, [MMP-14(EX-M0327-M02)]
• Two Key Residues in EphrinB3 Are Critical for Its Use as an Alternative Receptor for Nipah Virus, Oscar A. Negrete, Mike C. Wolf, Hector C. Aguilar, Sven Enterlein, Wei Wang, Elke Muhlberger, Stephen V. Su, Andrea Bertolotti-Ciarlet, Ramon Flick, Benhur Lee, PLoS Pathogens, February 2006 | Volume 2 | Issue 2 | e7, (Human ephrinB2 and ephrinB3 plasmids)
•  Intravascular Magnetic Resonance/Radiofrequency May Enhance Gene Therapy for Prevention of In-Stent Neointimal Hyperplasia, Fabao Gao, MD, PhD, Bensheng Qiu, PhD, Sourav Kar, MS, Xiangcan Zhan, PhD, Lawrence V. Hofmann, MD, and Xiaoming Yang, MD, PhD, Acad Radiol. 2006 April ; 13(4): 526–530 (VEGF165)
• Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling, Kevin E Fisher, Andreia Pop, Wonshill Koh, Nicholas J Anthis, W Brian Saunders and George E Davis, Molecular Cancer 2006, 5:69, [(MT1-MMP (EX-M0327-M02) and MT3-MMP (EX-Q0300-M02)]
• LEM2 is a novel MAN1-related inner nuclear membrane protein associated with A-type lamins, Andreas Brachner, Siegfried Reipert, Roland Foisner and Josef Gotzmann,  Journal of Cell Science 118, 5797-5810 (2005), [ LEM2 (#T5554)]
• The Protozoan Parasite Cryptosporidium parvum Possesses Two Functionally and Evolutionarily Divergent Replication Protein A Large Subunits, S. Dean Rider, Jr., Xiaomin Cai, William J. Sullivan, Jr., Aaron T. Smith, Jay Radke, Michael White, and Guan Zhu, J. Biol. Chem., Vol. 280, Issue 36, 31460-31469, September 9, 2005, [RPA1 (EX-B0001-B01)]
• Hepatocyte Growth Factor/Scatter Factor Differentially Regulates Expression of Proangiogenic Factors through Egr-1 in Head and Neck Squamous Cell Carcinoma, Brian Worden, Xin Ping Yang, Tin Lap Lee, Lorena Bagain, Ning T. Yeh, Joshua G. Cohen, Carter Van Waes and Zhong Chen, Cancer Research 65, 7071-7080, August 15, 2005, (Egr-1)
• HoxB2 binds mutant SOD1 and is altered in transgenic model of ALS, Jinbin Zhai, Hong Lin, Rafaela Canete-Soler and William W. Schlaepfer, Human Molecular Genetics 2005 14(18):2629-2640,  (HoxB2 in pReceiver-M01)
•  Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability, Alexandra Beilina, Marcel Van Der Brug, Rili Ahmad, Sashi Kesavapany, David W. Miller, Gregory A. Petsko, and Mark R. Cookson, PNAS April 19, 2005 vol. 102 no. 16 5703-5708, (PINK1 (residues 1–581) in Gateway entry clone)
• Ephrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus, Matthew I. Bonaparte, Antony S. Dimitrov, Katharine N. Bossart, Gary Crameri, Bruce A. Mungall, Kimberly A. Bishop, Vidita Choudhry, Dimiter S. Dimitrov, Lin-Fa Wang, Bryan T. Eaton, and Christopher C. Broder, PNAS July 26, 2005 vol. 102 no. 30 10652-1065, [ALCAM (Accn. NM_001627), and TM6SF1 (Accn. NM_023003)]
• Expression Profiling of ABC Transporters in a Drug-Resistant Breast Cancer Cell Line Using AmpArray, Yang Liu, Hui Peng, and Jian-Ting Zhang, Mol Pharmacol 68:430–438, 2005
• Radiofrequency-enhanced Vascular Gene Transduction and Expression for Intravascular MR Imaging–guided Therapy: Feasibility Study in Pigs1, Xiangying Du, MD, PhD, Bensheng Qiu, PhD, Xiangcan Zhan, PhD, Antonina Kolmakova, PhD, Fabao Gao, MD, PhD, Lawrence V. Hofmann, MD, Linzhao Cheng, PhD, Subroto Chatterjee, PhD, Xiaoming Yang, MD, PhD, Radiology 2005; 236:939–944, (VEGF-165)
• Application of microarrays to identify and characterize genes involved in attachment dependence in HeLa cells, Pratik Jaluria, Michael Betenbaugh, Konstantinos Konstantopoulos, Bryan Frank, and Joseph Shiloach, Metabolic Engineering, Volume 9, Issue 3 May 2007, Pages 241-251 (Full-length DNA constructs)
• A Conserved Na⁺ Binding Site of the Sodium-coupled Neutral Amino Acid Transporter 2 (SNAT2), Zhou Zhang, Thomas Albers, Heather L. Fiumera, Armanda Gameiro, and Christof Grewer, J. Biol. Chem., Vol. 284, Issue 37, 25314-25323, September 11, 2009 [SNAT2, C-YFP]
• Conversion of MDCK cell line to suspension culture by transfecting with human siat7e gene and its application for influenza virus production, Chia Chu, Vladimir Lugovtsev, Hana Golding, Michael Betenbaugh and Joseph Shiloach, PNASvol. 106 no. 35 14802-14807, September 1, 2009 [ V1581, C-eGFP tag]
• Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development, Kassiani Skouloudaki, Michael Puetz, Matias Simons, Jean-Remy Courbard, Christopher Boehlke, Björn Hartleben, Christina Engel, Marcus J. Moeller, Christoph Englert, Frank Bollig, Tobias Schäfer,  Haribaskar Ramachandran, Marek Mlodzik, Tobias B. Huber, E. Wolfgang Kuehn, Emily Kim,  Albrecht Kramer-Zucker and Gerd Walz, PNASvol. 106 no. 21 8579-8584, May 26, 2009[FRMD6, 3xFlag tag]
• Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission , Ruben K. Dagda, Salvatore J. Cherra, III, Scott M. Kulich, Anurag Tandon, David Park, and Charleen T. Chu,  J. Biol. Chem., Vol. 284, Issue 20, 13843-13855, May 15, 2009[Parkin, HA tag and PINK1, C-3xFlag tag]
• The Nucleocapsid Region of HIV-1 Gag Cooperates with the PTAP and LYPX_nL Late Domains to Recruit the Cellular Machinery Necessary for Viral Budding, Vincent Dussupt, Melodi P. Javid, Georges Abou-Jaoudé,  Joshua A. Jadwin,  Jason de La Cruz, Kunio Nagashima, and Fadila Bouamr,  PLoS Pathog.
  5(3): e1000339, March 2009 [CHMP4B, N-FLAG tag]
• An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases, Michael Hans Olma, Marcia Roy, Thierry Le Bihan, Izabela Sumara, Sarah Maerki, Brett Larsen, Manfredo Quadroni, Matthias Peter, Mike Tyers and Lionel Pintard, Journal of Cell Science122, 1035-1044, March 2009[Full-length Lrr1 entry clone]
• Strong Smooth Muscle Differentiation Is Dependent on Myocardin Gene Amplification in Most Human Retroperitoneal Leiomyosarcomas, Gaëlle Pérot, Josette Derré, Jean-Michel Coindre, Franck Tirode, Carlo Lucchesi, Odette Mariani, Laure Gibault, Louis Guillou, Philippe Terrier and Alain Aurias, Cancer Research 69, 2269, March 15, 2009 [EX-E0450-Lv06]
• Molecular Architecture of the Centriole Proteome: The Conserved WD40 Domain Protein POC1 Is Required for Centriole Duplication and Length Control, Lani C. Keller, Stefan Geimer, Edwin Romijn,  John Yates, III, Ivan Zamora, and Wallace F. Marshall,  Mol Biol Cell. 20(4): 1150–1166, February 15 2009 [Gateway Entry Clones for POC2 (GC-E0364), POC3 (GC-T7752), POC11 (GC-V0935), POC20 (GC-F0087), DIP13 (GC-Q0661), Hsp90 (GC-M0233), BUG11 (GC-U0139), BUG30 (GC-E0925), and BUG32 (GC-V1413)]
• Coronin-1 Is Associated with Neutrophil Survival and Is Cleaved during Apoptosis: Potential Implication in Neutrophils from Cystic Fibrosis Patients, Sandra Moriceau, Chahrazade Kantar, Julie Mocek, Noélie Davezac, Julie Gabillet, Ida Chiara Guerrera, Frank Brouillard, Danielle Tondelier, Isabelle Sermet-Gaudelus, Claire Danel, Gérard Lenoir, Soizic Daniel, Aleksander Edelman and Véronique Witko-Sarsat, The Journal of Immunology, 182, 7254 -7263, 2009 [pcDNA3, pcDNA3 coroHA-Nter, or pcDNA3coroHACter]
• Coatomer-dependent protein delivery to lipid droplets, Krishnakant G. Soni, Gonzalo A. Mardones, Rachid Sougrat, Elena Smirnova, Catherine L. Jackson and Juan S. Bonifacino, Journal of Cell Science 122, 1834-1841, 2009 [GFP-ADRP]
• Over-expression of EphB3 enhances cell–cell contacts and suppresses tumor growth in HT-29 human colon cancer cells, Sou-Tyau Chiu, King-Jen Chang, Chen-Hung Ting, Hsi-Che Shen, Hung Li and Fon-Jou Hsieh, Carcinogenesis, 30(9):1475-1486, 2009
  
• Differential Sorting of Human Parathyroid Hormone After Transduction of Mouse and Rat Salivary Glands, J. Adriaansen, P. Perez, C.M. Goldsmith, C. Zheng, and B.J. Baum, Hum Gene Ther. 19(10): 1021–1028, October 2008 [hPTH carrier plasmid]