NFκB transcriptional response element (TRE) Clone

NFkB TRE clone for NFkB signaling pathway
NFkB TRE clone for NFkB signaling pathway
Secreted alkaline phosphatase (SEAP)<br />Expression clone
Secreted alkaline phosphatase (SEAP)
Expression clone
Transcriptional response element(TRE) negative control clone
Transcriptional response element(TRE) negative control clone
GAPDH positive control clone
GAPDH positive control clone

NFkB TRE clone for NFkB signaling pathway Secreted alkaline phosphatase (SEAP)
Expression clone
Transcriptional response element(TRE) negative control clone GAPDH positive control clone

Price: $350.00 $395.00 $350.00 $375.00
Catalog#:
  • TR115
  • SEAP-PA01
  • TR001
  • GAPDH-PG02
Size: pEZX-PG02 pEZX-PA01 pEZX-PG02 pEZX-PG02
Qty:
Manual: DownloadDownload
View your cart


Introduction

GeneCopoeia’s GLuc-ON™ NFκB transcriptional response element (TRE) clone enables analysis of the activity of NFκB-regulated signal transduction pathways. NFκB is a transcription factor with may gene targets, such as B-cell Activating Factor, T-cell secreted factor, and chemokines. NFκB plays critical roles in immune system function, and its misregulation can lead to inlammatory diseases and cancer.

The GLuc-ON™ NFκB TRE clone contains tandem repeats of NFκB upstream of a minimal promoter and secreted Gaussia luciferase reporter gene, which allows robust and sensitive analysis without lysing the cells.  The NFκB response elements are engineered to provide strong activation with low background (Figure 1). The GLuc-ON™ NFκB TRE clone is provided as transfection-ready DNA. Negative (non-activating), positive (constitutively-activted) and normalization (secreated alkaline phosphatase) control clones are also available for purchase.