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VividFISH Disease Gene FISH Probes

Bright fluorescent probes for disease gene-specific detection.

Introduction

 

GeneCopoeia's VividFISH™ fluorescence in situ hybridization (FISH) locus-specific probes are the ideal tools for disease gene detection. FISH gene-specific probes are extremely valuable for diagnosis and/or prognosis of disease with chromosomal abnormalities, gene amplification, or gene depletion.

Advantages

  • Exceptionally bright fluorescent probes make gene detection easy and convenient.
  • Probed are contained in mixes for fluorescence in two colors (green and orange).
  • Pretreatment kit for FFPE samples also available.

 

Order VividFISH™ disease gene probes

Click on the expandable menus below to display ordering options for each VividFISH™ disease gene probe. Each probe is provided with hybridization buffer.

The VividFISH™ ALK break apart probe set detects aberrant translocations of parts of the ALK gene on chromosome 2p23 (NCBI GeneID:238) with the echinoderm microtubule-associated protein-like 4 gene (EML4) on chromosome 2p21 (NCBI GeneID: 27436). This results in the generation of EML4-ALK fusion proteins that are associated with non-small cell lung carcinoma. The VividFISH™ ALK break apart probe set provides a valuable tool for diagnosis of non-small cell lung carcinoma in human lung tissue samples.

Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.

Buy Catalog # Description Color Quantity Price
FP501 VividFISH™ probe set for ALK break apart Green (5')/orange (3') 10 hybridizations $750

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   

The VividFISH™ CEP17/HER2 probe set detects aberrant amplification of the HER2 gene on chromosome 17 (NCBI GeneID:2064). Amplification  of HER2 is associated with poor survival from breast cancer. The VividFISH™ CEP17/HER2 probe set, which is a combination of one probe detecting the HER2 gene and a second control probe detecting the centromere of chromosome 17, provides a valuable tool for determining the prognosis of breast cancer and guiding subsequent treatment regimens.

Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.

Buy Catalog # Description Color Quantity Price
FP502 VividFISH™ probe set for CEP17/HER2 Green (CEP17)/orange (HER2) 10 hybridizations $700

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   

The VividFISH™ CEP07/c-MET probe set detects aberrant rearrangement of the c-MET gene on chromosome 7 (NCBI GeneID:4233). Activation of c-MET, a well-characterized proto-oncogene, is associated with poor survival in  many cancer types, including those of the liver, kidney, stomach, breast, colon, and brain. The VividFISH™ CEP07/c-MET probe set, which is a combination of one probe detecting the c-MET gene and a second control probe detecting the centromere of chromosome 7, provides a valuable tool for determining the prognosis of a variety of cancers and guiding subsequent treatment regimens.

Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.

Buy Catalog # Description Color Quantity Price
FP503 VividFISH™ probe set for CEP07/MET Green (CEP07)/orange )MET) 10 hybridizations $700

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   

The VividFISH™ CEP07/EGFR probe set detects aberrant amplification of the EGFR gene on chromosome 7 (NCBI GeneID:1956). Activation of EGFR, a well-characterized proto-oncogene, is associated with many cancer types, including those of the lung and breast. The VividFISH™ CEP07/EGFR probe set, which is a combination of one probe detecting the EGFR gene and a second control probe detecting the centromere of chromosome 7, provides a valuable tool for diagnosis of cancers in a variety of tissues.

Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.

Buy Catalog # Description Color Quantity Price
FP504 VividFISH™ probe set for CEP07/EGFR Green (CEP07)/orange (EGFR) 10 hybridizations $700

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   

The VividFISH™ CEP10/PTEN probe set detects aberrant loss of the phosphatase and tensin homolog (PTEN) gene on chromosome 10 (NCBI GeneID:5728). Loss of PTEN, a tumor suppressor, is associated with many cancer types, including those of the brain and breast. The VividFISH™ CEP10/PTEN probe set, which is a combination of one probe detecting the PTEN gene and a second control probe detecting the centromere of chromosome 10, provides a valuable tool for diagnosis of cancers in a variety of tissues.

Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.

Buy Catalog # Description Color Quantity Price
FP505 VividFISH™ probe set for CEP10/PTEN Green (CEP10)/orange (PTEN) 10 hybridizations $700

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

 

Order VividFISH™ chromosome enumeration probes (CEP)

CEP probes are valuable as controls for LSI or gene-specific probes. CEPs can also be used as standalone probes to detect gross chromosomal abnormalities. Click on the expandable menus below to display ordering options for each VividFISH™ chromosome enumeration probe. Each probe is provided with hybridization buffer.

Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP001 FISH CEP probe for human chromosome 1-green Green 10 hybridizations $225
FP002 FISH CEP probe for human chromosome 1-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP006 FISH CEP probe for human chromosome 2-green Green 10 hybridizations $225
FP007 FISH CEP probe for human chromosome 2-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP011 FISH CEP probe for human chromosome 3-green Green 10 hybridizations $225
FP012 FISH CEP probe for human chromosome 3-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP016 FISH CEP probe for human chromosome 4-green Green 10 hybridizations $225
FP017 FISH CEP probe for human chromosome 4-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP021 FISH CEP probe for human chromosome 5-green Green 10 hybridizations $225
FP022 FISH CEP probe for human chromosome 5-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP025 FISH CEP probe for human chromosome 6-green Green 10 hybridizations $225
FP026 FISH CEP probe for human chromosome 6-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP031 FISH CEP probe for human chromosome 7-green Green 10 hybridizations $225
FP032 FISH CEP probe for human chromosome 7-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP036 FISH CEP probe for human chromosome 8-green Green 10 hybridizations $225
FP037 FISH CEP probe for human chromosome 8-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP041 FISH CEP probe for human chromosome 9-green Green 10 hybridizations $225
FP042 FISH CEP probe for human chromosome 9-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP046 FISH CEP probe for human chromosome 10-green Green 10 hybridizations $225
FP047 FISH CEP probe for human chromosome 10-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP051 FISH CEP probe for human chromosome 11-green Green 10 hybridizations $225
FP052 FISH CEP probe for human chromosome 11-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP056 FISH CEP probe for human chromosome 12-green Green 10 hybridizations $225
FP057 FISH CEP probe for human chromosome 12-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP061 FISH CEP probe for human chromosome 13-green Green 10 hybridizations $225
FP062 FISH CEP probe for human chromosome 13-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP066 FISH CEP probe for human chromosome 14-green Green 10 hybridizations $225
FP067 FISH CEP probe for human chromosome 14-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP071 FISH CEP probe for human chromosome 15-green Green 10 hybridizations $225
FP072 FISH CEP probe for human chromosome 15-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP076 FISH CEP probe for human chromosome 16-green Green 10 hybridizations $225
FP077 FISH CEP probe for human chromosome 16-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP081 FISH CEP probe for human chromosome 17-green Green 10 hybridizations $225
FP082 FISH CEP probe for human chromosome 17-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP086 FISH CEP probe for human chromosome 18-green Green 10 hybridizations $225
FP087 FISH CEP probe for human chromosome 18-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP091 FISH CEP probe for human chromosome 19-green Green 10 hybridizations $225
FP092 FISH CEP probe for human chromosome 19-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP096 FISH CEP probe for human chromosome 20-green Green 10 hybridizations $225
FP097 FISH CEP probe for human chromosome 20-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP101 FISH CEP probe for human chromosome 21-green Green 10 hybridizations $225
FP102 FISH CEP probe for human chromosome 21-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP106 FISH CEP probe for human chromosome 22-green Green 10 hybridizations $225
FP107 FISH CEP probe for human chromosome 22-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP111 FISH CEP probe for human chromosome X-green Green 10 hybridizations $225
FP112 FISH CEP probe for human chromosome X-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download
   

   
Click on the product description to view images of fluorescent signals resulting from hybridization of the selected VividFISH™ probe with mammalian chromosomes.
Buy Catalog # Description Color Quantity Price
FP116 FISH CEP probe for human chromosome Y-green Green 10 hybridizations $225
FP117 FISH CEP probe for human chromosome Y-orange Orange 10 hybridizations $225

 

 

   
Buy Catalog # Description Quantity Price User manual
FP204 VividFISH™ FFPE pretreatment kit 10 reactions $150 Download