GeneCopoeia is the original manufacturer of human and mouse expression-ready, full-length ORF cDNA clones. Researchers worldwide have depended on GeneCopoeia OmicsLink™ cDNA clones to accelerate their research. OmicsLink expression-ready ORF cDNA clones are ready for immediate in vivo and in vitro expression. Experience real value with expression-ready clones that save you time and money. Get results faster and publish sooner.
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Express in E. coli, mammalian cells or other common cell types
Express in vitro with high success with cell-free translation systems.
Use tags for protein purification and production
Use tags for purification detection and wide range of functional assays
Generate in situ hybridization probes for tissue or organ expression profiling
Restore gene functions for shRNA or miRNA functional validation studies
High-throughput content and screening
Uniformity and high-quality clone sets make them ideal for large-scale high content and high-throughput screening studies in functional genomics, proteomics and systems biology.
Popular tags and technologies
Lentiviral technology — Enables high efficiency gene delivery to virtually all cell types and whole model organisms resulting in high expression levels of delivered genes.
Internal ribosome entry site (IRES) technology — Allows coordinated and efficient co-expression of two genes with the same promoter in a single vector. When reporter and target genes are simultaneously expressed, biological activities of the target proteins are minimally affected.
HaloTag® technology — This novel multi-functional protein tag binds covalently and specifically to a variety of synthetic ligands, enabling tagged proteins to be labeled with fluorophores for in vitro or in vivo imaging or with affinity agents for purification.
AviTag™ technology — Based on site-specific in vitro or in vivo biotinylation of a short tag sequence enabling specific or reversible binding of avidin or streptavidin to biotin for immobilization, purification and visualization of the tagged target proteins.
Cell-free technology — Enables high success rate of target protein expression and natural protein folding with high percentage of active proteins. Proteins that are potentially toxic to cells can also be produced using the cell free system.
OmicsLink ORF cDNA clones are derived from full-length human and mouse genes that were chosen through a strict selection process. This process includes the extraction, comparison as well as validation of gene sequences and annotation information from multiple public and private sources; clustering and reduction of redundant gene sequences, filtering out error sequences or sequencing errors plus several other manual curation steps.
Following this stringent selection process, the entire coding open reading frames (ORFs) were generated from sequence validated full-length cDNA clones or high-quality human tissue cDNA libraries to construct expression-ready clones.
Once the clone is constructed, GeneCopoeia follows additional quality control process to ensure the right clone is delivered to our customers.
All ORFs are fully sequenced.
PCR amplification and size validation
Enzyme digestion check of the integrity of whole plasmid.
