Resources

Genome Editing: Cas9 Stable Cell Lines for CRISPR sgRNA Validation, Library Screening, and More

  Ed Davis, Ph.D. Introduction The CRISPR-Cas9 system has become greatly popular for genome editing in recent years, due to its ease-of-design, efficiency, specificity, and relatively lo...

Using GeneCopoeia FISH Probes in a CRISPR-mediated Genome Editing Workflow

  Qihong Xu, Meng Zhang, Xueming Xu, and Ed Davis Introduction Immortalized mammalian cell lines, while providing convenient model systems for biomedical and pharmaceutical re...

Genome Editing: Applications For GeneCopoeia CRISPR sgRNA Libraries

  Ed Davis, Ph.D. Biomedical researchers are enjoying a Renaissance in functional genomics, which aims to use a wealth of DNA sequence information—most notably, the complete sequence ...

Genome Editing: HDR Donors For Gene Knockout, Mutagenesis, Tagging, and Safe Harbor Knock-in

  Ed Davis, Ph.D. Genome Editing—making specific changes at targeted genomic sites—is fundamentally important to researchers in biology and medicine (Bogdanove & Voytas, 201...

Lentivirus: That’s My MOI, and I’m Sticking To It

  Ed Davis, Ph.D. Introduction Lentiviral vectors have proven invaluable for introducing genetic material into mammalian cells, either in culture or whole animals (reviewed in Mát...

ORF clones: many tags, many decisions

  Ed Davis, Ph.D. Introduction Fusion tagging-the practice of adding amino acids in-frame to one end of a native protein-is a well- established strategy for many applications, including ...

Genome Editing: Which Should I Choose, TALEN or CRISPR?

  Ed Davis, Ph.D. Introduction Genome Editing-the ability to make specific changes at targeted genomic sites-is of fundamental importance to researchers in biology and medicine (Bogdanov...

Genome Editing in Mammalian Cells: What Do I Do Next?

  Ed Davis, Ph.D. Genome Editing-the ability to make specific changes at targeted genomic sites-is of fundamental importance in biology and medicine (for reviews, see Bogdanove & Voytas...

CRISPR-Cas9 Specificity: Taming Off-target Mutagenesis

  Ed Davis, Ph.D. Abstract Genome Editing-the ability to make specific changes at targeted genomic sites in complex organisms-is of fundamental importance in biology and medicine (Bogdan...

Genome Editing Technology From GeneCopoeia, Inc.

  Ed Davis, Ph.D. Abstract Genome Editing-the ability to make specific changes at targeted genomic sites-is fundamentally important to researchers in biology and medicine (Bogdanove &...

Knockout by TALEN or CRISPR vs. Knockdown by shRNA or siRNA

  Ed Davis, Ph.D. Recent advances in technologies for genome editing-the use of TALEN or CRISPR to make targeted, permanent changes to genes-have revolutionized molecular genetics. They hav...

GeneCopoeia Genome Editing Tools for Safe Harbor Integration in Mice and Humans

  Ed Davis, Liuqing Qian, Ruiqing lI, Junsheng Zhou, and Jinkuo Zhang Introduction The ability to introduce transgenes into biological systems, such as cultured cells or animals, is of f...

Technical and Application Notes

CRISPR & TALEN   Technical notes Knockout By TALEN Or CRISPR vs. Knockdown By shRNA or siRNA CRISPR-Cas9 Specificity: Taming Off-target Mutagenesis Genome Editing: Which Should I Choose, TALEN Or CRISP...

Recorded Webinars

Genome Editing Title: Genome Editing: How Do I Use CRISPR? Presented Wednesday, December 21, 2016 Genome Editing-the ability to make specific changes at targeted genomic sites-is fundament...

Warranty Statements

Warranty Statements   cDNA clones: ORF cDNA Expression Clones   ORFeome Collaboration Clones miRNA: miTarget™ microRNA 3' UTR target clones ...

Brochures and Product Profiles

Product Line   cDNA clones: ORF cDNA Expression Clones   Expression Technologies –HaloTag®, AviTag™ , IRES miRNA: microRNA Solutions ...

OmicsLink™ Expression-Ready ORF cDNA Vectors

Expression-ready so no further sub cloning necessary Sequence-verified and available for 40,000+ human and mouse genes Choices of 150+ expression vectors as listed in the tables below ...

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